Science & Practice
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Enzyme immunoassay toxin-positive cases associated with more severe, recurrent disease than NAAT-positive-only cases, but both methods linked to comparable mortality, complications outcomes.
Elevated levels are associated with increased mortality risk, especially in young adults.
Considerations in reporting incidental sickle cell trait findings from routine A1C testing.
AACC urges open communications between laboratory professionals and clinicians to prevent this potentially harmful test confounder.