In U.K. women age 50 or older levels above 35 U/mL yield solid threshold positive predictive value for ovarian and other cancers.

The original poster’s lab recently changed to 2 decimal places, but he noticed that major reference labs vary a lot in how many decimal places they report (from 1 to 3) and is wondering what other labs do. A couple respondents say that labs should not report out to 3 decimal places unless they’ve validated PSA results to that decimal place. Another respondent provided a link to a paper on this issue that concludes that each lab must perform independent statistical analysis to determine the appropriate significant figure limitations for clinically relevant analytes such as PSA.

Dietary supplements containing vitamin D and fish oil with omega-3 fatty acids do not reduce signs of systemic inflammation linked to many chronic diseases, according to a recent study.