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Certificate Program

Fundamentals of Molecular Pathology Certificate Program

  • Credit: 11.0 ACCENT
  • Level: Intermediate

Price: $500.00

Member Price: $250.00


Developed with all levels of laboratory professionals in mind, the content of this program is at the basic to intermediate level and will provide participants with opportunities to increase their knowledge of diagnostic applications of molecular pathology. This program was developed to present the essentials of molecular pathology and provide laboratorians with an understanding of nine different areas of study.

This program is composed of nine courses, listed below. Each course can be completed online in 1-2 hours each and contains lectures, reference materials and a quiz. Communicate questions or comments using the program discussion board.


  1. Introduction to Molecular Biology
    • Learning Objectives: The learner will be able to list sample requirements, name methods to isolate the DNA, and discuss of the general principles of Southern blotting, PCR, and signal amplification.
    • Speaker: John Greg Howe, PhD, DABCC, Yale University School of Medicine, New Haven, CT
  2. Molecular Laboratory Techniques
    • Learning Objectives: The learner will be able to understand different sample types used for nucleic acid testing, discuss DNA and RNA isolation and measurement techniques, describe the basics of gel electrophoresis of nucleic acids, the principles of the polymerase chain reaction and other nucleid acid amplification methods, as well as signal amplification and real time PCR.
    • Speaker: John Greg Howe, PhD, DABCC, Yale University School of Medicine, New Haven, CT
  3. Next Generation Sequencing and Bioinformatics
    • Learning Objectives: Learners will be able to discuss the advantages of NGS, steps in NGS methodology, and summarize different types of NGS assays.
    • Speaker: Christina Lockwood, PhD, University of Washington, Seattle, WA
  4. Introduction to Molecular Genetics
    • Learning Objectives: The learner will be able to describe different modes of inheritance for single gene disorders, define important molecular genetics terminology, describe types of genetic variants and discuss non-Mendelian patters of inheritance.
    • Speaker: Linnea Baudhuin, PhD, Mayo Clinic, Rochester, MN
  5. Molecular Methods for Infectious Diseases
    • Learning Objectives: The learner will be able to list the advantages and disadvantages of molecular testing for infectious agents, discuss the reasons for molecular testing of infectious diseases, and explain viral load and disease progression.
    • Speakers: Roberta Madej, PhD, QTMB, Scotland UK & Deborah Payne, PhD, American Pathology Partners/UniPath, Denver, CO
  6. Hematopathology
    • Learning Objectives: The learner will be able to discuss the need for molecular markers in monitoring cancer, how molecular markers can be used to identify treatment regimens, and explain the use of molecular markers in minimal residual disease.
    • Speaker: Barbara Zehnbauer, PhD, Emory University, Atlanta, GA
  7. Molecular Signatures for Oncology
    • Learning Objectives: The learner will be able to define solid tumors, explain why molecular diagnostics are used to diagnose solid tumors, and discuss specimen samples when doing molecular testing of solid tumors.
    • Speaker: Neal Lindeman, MD, DABCC, Brigham and Women's Hospital, Boston, MA
  8. Lab Practices
    • Learning Objectives: The learner will be able to explain issues in quality control and quality assurance, discuss how to design and staff a laboratory that performs molecular diagnostics, and explain some of the regulatory issues regarding molecular pathology.
    • Speaker: Andrea Ferreira-Gonzalez, PhD, Virginia Commonwealth University, Richmond, VA
  9. Validation for Molecular Assays in Oncology
    • Learning Objectives: The learner will understand the process of analytical and clinical verification and validation of assays used in molecular diagnostics, and identify the key characteristics needed for validation of NGS assays in oncology.
    • Speaker: Helen Fernandes, PhD, Columbia University Medical Center, New York, NY

Launch Year: 2010
Review Year: 2016
Re-launch Year: 2017
Course Number: 12422


Developed in cooperation with the AACC Molecular Pathology Division.