Cytokine storm syndrome (CSS) in an umbrella term for a potentially fatal immune response associated with a variety of conditions and triggers. It is known by many names, including macrophage activation syndrome (MAS) when associated with rheumatic diseases, or familial hemophagocytic lymphohistiocytosis (HLH) as a genetic condition that most often affect infants. Many common forms of CSS are often triggered by infections, particularly viruses, of which Covid-19 appears to be included. In this webinar, Dr. Randy Cron will discuss criteria for identifying CSS in patients, complications, and available treatments which include glucocorticoids, but also targeted therapies that dampen pro-inflammatory cytokines like interleukin-1 (IL-1) and IL-6.
At the end of this activity, participants will be able to
- Recognize the variety of conditions that can be complicated by cytokine storm syndrome.
- Calculate the probability of a cytokine storm syndrome using various proposed criteria.
- Compare and contrast the various treatment modalities available for cytokine storm syndrome.
Randy Cron, MD, PhD
Professor of Pediatrics & Medicine
Director, Division of Pediatric Rheumatology
Children's Hospital of Alabama/
University of Alabama at Birmingham
This activity is approved for 1.25 ACCENT continuing education credits. Activity ID# 1998. This activity was planned in accordance with ACCENT Standards and Policies.