DOI: 10.1373/clinchem.2013.204438

Summary: 

A 60-year-old man presented to his general practitioner with complaints of indigestion and flu-like symptoms. The results of a clinical examination were unremarkable. The only abnormality found in routine hematology and biochemistry investigations was an increased serum alkaline phosphatase concentration (131 U/L; reference interval, 35–120 U/L).