A 72-year-old white woman underwent a routine annual physical examination. She had no history of diabetes, cardiovascular disease, cancer, or chronic inflammatory condition. She smoked, had hypertension (systolic blood pressure 145 mm Hg), and was being treated with an angiotensin-converting–enzyme inhibitor. She was on no other medications. Physical examination was unremarkable. She was thin with a body mass index of 23 kg/m2.