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Issue

Thursday, May 7, 2020


In The News


Serology tests that detect SARS-CoV-2 virus antibodies (immunoglobulin A/G/M) have proliferated as society looks for ways to relax quarantine restrictions. Such tests might help track community spread of SARS-CoV-2 virus and determine whether plasma donated by patients who have recovered from COVID-19, the illness caused by SARS-CoV-2, could help still…
Very few patients with resistant hypertension who meet criteria for primary aldosteronism (PA) are getting screened for this condition. This underscores the need to boost guideline-recommended screening and targeted therapies, according to the authors of a study published in Hypertension.

AACC Alert


A study in Clinical Chemistry calls into question the link between osteoporotic fractures and low vitamin D levels. While the researchers found an association between low plasma 25-hydroxyvitamin D and fractures, a Mendelian randomization analysis revealed no causal role for this marker in fracture risk.

Inside AACC


Point-of-care tests (POCT) are growing in demand, but quality concerns remain despite available standards and practice guidelines. A survey of POCT users revealed a number of key needs: instruments that facilitate rapid, automatic, quality-ensured POCT results, and more insight and guidance on the entire testing process, including result interpretation.

World View


A high-resolution melting analysis-based test (HRM) shows promise as a rapid, inexpensive screening tool for recurrent pregnancy loss (RPL). Tested on more than 700 products-of-conception (POC) samples, HRM showed high sensitivity, specificity, and positive predictive value (PPV), and also improved cost-effectiveness when used in conjunction with other tests.