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Features


A look at the history of Human Leukocyte Antigen testing highlights how methods have changed since the 1960s. While the idea that a transplant donor and recipient must be compatible for a successful procedure, the meaning behind compatibility has evolved over time.
Laboratories around the country are dropping the race modifier in estimated glomerular filtration rate calculations of kidney function. The National Kidney Foundation and American Society for Nephrology Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Diseases mentions that the new formula does not include race in the…
Maternal-fetal medicine owes much of its successes in recent decades to the contributions of the clinical laboratory. Yet recent controversy around noninvasive prenatal screening shows that laboratorians have work to do in order to ensure clinicians can translate advances in medical technology into better patient care.

Ask the Expert


Bench Matters


Although most contemporary immunoassays are extremely robust and display excellent sensitivity and specificity, they are still susceptible to interferences. It is critical that laboratories have the ability both to detect and rule out assay interference as a source of error.

Industry Playbook


Laboratory Stewardship


Supply chain challenges have plagued the clinical laboratory throughout the COVID-19 pandemic. Increased, unpredictable demand for laboratory testing has coincided with global delays and raw material shortages. The pandemic exposed the weaknesses of “just in time” inventory management, leaving many laboratories without inventory. Laboratories worldwide have endured alternating shortages, from…
Patient blood management (PBM) is a multimodality, multidisciplinary approach to stewardship in transfusion medicine. It involves optimization of anemia and hemostasis with a goal of avoiding unnecessary transfusions. Now considered standard of care, PBM is patient-centered and can improve quality while reducing costs. The recent intermittent national blood shortages make…

Regulatory Roundup


The Sample