Biotin and Laboratory Testing: Recognizing Interferences and Preventing Misdiagnosis

  • Duration: 60 minutes
  • Date:SEP.28.2017 2:00 PM - 03:00 PM

Price: $0.00

Member Price: $0.00

Rating: Member Average

All webinar times are in Eastern Time except where noted. Convert to your timezone.


This webinar is being presented as a collaboration between the Society for Young Clinical Laboratorians (SYCL) and AACC's Endocrinology Division and presents a trending laboratory medicine topic through the viewpoint and expertise of an aspiring lab leader.

Biotin, a water-soluble B-complex vitamin, is found in numerous foods and over-the-counter multi-vitamins and supplements for hair, skin, and nails. Recent findings have discovered that the presence of exogenous biotin in blood samples can interfere with laboratory test results. Labs need to be aware of these findings since many FDA-cleared, automated immunoassays allow for the rapid measurement of analytes through biotin-streptavidin interactions.

Join us for this webinar with speakers Nikola Baumann, Ph.D. and Brooke Katzman, Ph.D., of the Mayo Clinic, who will present several compelling cases of patients identified with erroneous thyroid function test results due to biotin consumption.

Drs. Baumann and Katzman will describe current trends in biotin consumption and the pervasive use of biotin in immunoassay reagents. They will also outline key strategies for labs to prevent potentially serious patient safety incidents in an era of widespread biotin supplementation.


photograph of nicola bauman smallerNikola A. Baumann, Ph.D.
Director, Central Clinical Laboratory and Central Processing
Assistant Professor, Laboratory Medicine and Pathology
Mayo Clinic, Rochester, MN

photograph of brooke katzman Brooke M. Katzman, Ph.D.
Co-Director, Hospital Clinical Laboratory and Point of Care
Mayo Clinic, Rochester, MN

Learning Objectives

After participating in this webinar, you should be able to:

  1. Describe trends in biotin supplementation for therapeutic and nutraceutical purposes.
  2. Recognize the potential impact of biotin consumption on some immunoassay-based laboratory test results.
  3. Develop strategies to prevent misdiagnosis and mitigate patient safety risks from biotin interferences in lab testing.

Target Audience

Laboratory directors, managers, and supervisors; residents/trainees, industry professionals involved in rapid immunoassay testing methods.

Continuing Education Credit

AACC designates this activity for a maximum of 1.0 ACCENT® credit hours towards the AACC Clinical Chemist’s Recognition Award. AACC is an approved provider of continuing education (CE) for clinical laboratory scientists licensed in states that require documentation of CE, including California, Florida, Louisiana, Montana, Nevada, North Dakota, Rhode Island, Tennessee, and West Virginia. ACCENT® credit is also recognized by several organizations: AAB, ABCC, ACS, AMT, ASCLS, ASCP, ASM, CAP, IFCC, and NRCC.

Registration Information

  • Registration covers one phone line and one computer connection for the webinar. 
  • Several business days prior to the webinar, AACC will e-mail instructions to the registrant on how to participate, including a phone number to call to listen to the audio portion of the webinar and a URL where you can log in for the visual portion of the webinar

Technical requirements

AACC uses WebEx to conduct its webinars. To attend the webinar, you will need:

  • A separate telephone line for the audio or a sound card and speakers
  • A 56Kbps Internet connection or better
  • Windows Users - Internet Explorer 6/7, Firefox 2, Mozilla 1.7+, Netscape 8.1 or higher.
  • Mac Users - Firefox 2, Safari 3.0 (Mac OS 10.4,10.5), Safari 2.0 (Mac OS 10.4) Safari 1.3 (Mac OS 10.3).
  • Linux Users - Firefox 2, Mozilla 1.7 or higher.

NOTE: The WebEx plug-in will not install if your browser has high security settings or you do not have administrative rights on your PC

To test your system, please try joining a test meeting prior to your webinar at: https://www.webex.com/lp/jointest. Once on the site, enter your name and email address and click "join."

Information for attendees outside of the United States

If you are outside of the U.S., we recommend that you listen to the webinar via your computer speakers. If for some reason the webinar is not being broadcast over your computer speakers, and you do have high-speed internet and a Skype* subscription on your computer, you can use Skype for the phone portion of the webinar as a way to avoid charges from your phone company. Just call in to the US number using Skype.

*If you do intend to use Skype, you also still need to access the computer portion of the webinar as described above. If you want to use Skype but do not have a subscription or would like more information, visit www.skype.com.

Supported By

abbott diagnostics

Roche 2014 Logo