Biotin and Laboratory Testing: Recognizing Interferences and Preventing Misdiagnosis

  • Duration: 60 minutes
  • Date:SEP.28.2017 2:00 PM

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This webinar is being presented as a collaboration between the Society for Young Clinical Laboratorians (SYCL) and AACC's Endocrinology Division and presents a trending laboratory medicine topic through the viewpoint and expertise of an aspiring lab leader.

Biotin, a water-soluble B-complex vitamin, is found in numerous foods and over-the-counter multi-vitamins and supplements for hair, skin, and nails. Recent findings have discovered that the presence of exogenous biotin in blood samples can interfere with laboratory test results. Labs need to be aware of these findings since many FDA-cleared, automated immunoassays allow for the rapid measurement of analytes through biotin-streptavidin interactions.

Join us for this webinar with speakers Nikola Baumann, Ph.D. and Brooke Katzman, Ph.D., of the Mayo Clinic, who will present several compelling cases of patients identified with erroneous thyroid function test results due to biotin consumption.

Drs. Baumann and Katzman will describe current trends in biotin consumption and the pervasive use of biotin in immunoassay reagents. They will also outline key strategies for labs to prevent potentially serious patient safety incidents in an era of widespread biotin supplementation.


photograph of nicola bauman smallerNikola A. Baumann, Ph.D.
Director, Central Clinical Laboratory and Central Processing
Assistant Professor, Laboratory Medicine and Pathology
Mayo Clinic, Rochester, MN

photograph of brooke katzman Brooke M. Katzman, Ph.D.
Co-Director, Hospital Clinical Laboratory and Point of Care
Mayo Clinic, Rochester, MN

Learning Objectives

After participating in this webinar, you should be able to:

  1. Describe trends in biotin supplementation for therapeutic and nutraceutical purposes.
  2. Recognize the potential impact of biotin consumption on some immunoassay-based laboratory test results.
  3. Develop strategies to prevent misdiagnosis and mitigate patient safety risks from biotin interferences in lab testing.

Target Audience

Laboratory directors, managers, and supervisors; residents/trainees, industry professionals involved in rapid immunoassay testing methods.

More Information

Continuing Education Credit

AACC designates this activity for a maximum of 1.0 ACCENT  ® credit hours towards the AACC Clinical Chemist’s Recognition Award. AACC is an approved provider of continuing education (CE) for clinical laboratory scientists licensed in states that require documentation of CE, including California, Florida, Louisiana, Montana, Nevada, North Dakota, Rhode Island, Tennessee, and West Virginia. ACCENT  ® credit is also recognized by several organizations: AAB, ABCC, ACS, AMT, ASCLS, ASCP, ASM, CAP, IFCC, and NRCC.

To claim ACCENT ® credit for this event, please send a request to education@aacc.org.

Supported By

abbott diagnostics

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