Using the HbA1c Test Wisely in Clinical Practice

  • Duration: 1 Hour 30 Minutes
  • Date:NOV.4.2015 2:00 PM - 03:30 PM

Price: $0.00

Member Price: $0.00


HbA1c is routinely used in the management of diabetes to monitor long term glycemic control and assess the risk of developing complications.  It has also recently been recommended for use in the diagnosis of diabetes.

And while A1c is a commonly ordered test, A1c testing can be a tricky proposal, including the possibility that Hb variants and adducts may affect the accuracy of your HbA1c method.  Each method must be evaluated for potential interference in the presence of the most common heterozygous variants and other known interferents.

This presentation will show labs how best to assess interferences, results from several interference studies, and general recommendations about interpretation of test results.


This program is designed for laboratory managers, supervisors, and directors; point-of-care coordinators and supervisors; and other healthcare professionals involved in performing or managing HbA1c testing.


Randie R. Little, PhD, Professor, Departments of Pathology & Anatomical Sciences and Child Health and Director, Diabetes Diagnostic Laboratory, University of Missouri (Columbia, MO)

Steven D. Wittlin, MD, Clinical Director, Endocrine-Metabolism Division and Director, Diabetes Service, University of Rochester Medical Center (Rochester, NY)


Because of recent changes in best practices for use of HbA1c testing, as well as the wide availability of numerous test methods, it’s important for lab professionals to know how to ensure the accuracy and clinical utility of HbA1c results.

Learning Objectives:

  1. Identify the four most common hemoglobin variants worldwide.
  2. Describe how HbA1c is influenced by biological and analytical factors.
  3. Describe a study to evaluate interference of common variants with HbA1c
  4. Explain how a specific Hb variant can interfere with one HbA1c method but not another
  5. Evaluate the reliability of converting HbA1c results to estimated average glucose

Drs. Little and Wittlin will answer participant questions during a live Q&A at the end of the webinar.

Technical Requirements

AACC uses WebEx to conduct its webinars. To attend the webinar, you will need:

  • A separate telephone line for the audio or a sound card and speakers
  • A 56Kbps Internet connection or better
  • Windows Users - Internet Explorer 6/7, Firefox 2, Mozilla 1.7+, Netscape 8.1 or higher.
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  • Linux Users - Firefox 2, Mozilla 1.7 or higher.

NOTE: The WebEx plug-in will not install if your browser has high security settings or you do not have administrative rights on your PC

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