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Designs for Clinical Trials: Perspectives on Current Issues

Designs for Clinical Trials
  • Copyright:2012
  • ISBN:9781461401391
  • Pages:204

Price: $189.00

Member Price: $189.00

Rating: Member Average


  • Each chapter will be written by an expert conducting research in the topic of that chapter.

  • This book examines current issues and controversies in the design of clinical trials, including topics in adaptive and sequential designs, the design of correlative genomic studies, and the design of studies in which missing data is anticipated.

  • The chapters serve as a guidance for statisticians designing trials.

Statistical methods for clinical trials have been an area of active research in Biostatistics since the first modern clinical trials were mounted in 1946 by the British Medical Research Council in whooping cough and tuberculosis. Often, the participants in clinical trials suffer from potentially fatal chronic diseases, and it is especially important that these experiments in medical research use designs that are efficient, can be understood by physicians, policy makers and patients, respond quickly new ideas in medicine and statistics, and, perhaps above all, show respect for the complex and important ethical issues that arise in these settings.