2022
Women in Laboratory Medicine: A Q&A on Diversity and Inclusion
A Paradigm Shift: Engagement of Clinical Chemistry and Laboratory Medicine Trainees by Innovative Teaching Methods
- Moderators: Joesph R. Wiencek, Allison B. Chambliss
- Experts: Roger L. Bertholf, Steven W. Cotten, Christina Ellervik, Justin D. Kreuter, Kamran M. Mirza, Zahra Shajani-Yi
- DOI: https://doi.org/10.1093/clinchem/hvac036
Interpreting EQA—Understanding Why Commutability of Materials Matters
Pregnancy in the Time of COVID-19: What Are the Challenges for Maternity Care?
Alternative Sample Matrices Supporting Remote Sample Collection during the Pandemic and Beyond
At-Home Testing for Infectious Diseases: The Laboratory Where You Live
2021
Molecular Approaches to Transplant Monitoring; Is the Horizon Here?
Perspectives on Identifying and Treating Familial Hypercholesterolemia in Childhood
- Moderators: Sarah D. de Ferranti, Dhruv S. Kazi
- Experts: Kirsten Bibbins-Domingo, Stephen Daniels, Barbara Howaniec, Amit V. Khera, Thomas B. Newman, Louis Vernacchio
- DOI: https://doi.org/10.1093/clinchem/hvab157
Data Mining Approaches to Reference Interval Studies
Current Utility and Reliability of Biological Variability
Current Testing Strategies for SARS-CoV-2 in the United States
Evolution of Blood Sample Transportation and Monitoring Technologies
Centralized vs Decentralized Molecular Infectious Disease Testing
Is It Time to Move On? Reexamining Race in Glomerular Filtration Rate Equations
Should LC-MS/MS Be the Reference Measurement Procedure to Determine Protein Concentrations in Human Samples?
How Can Routine Clinical Laboratories Keep Up with the Opioid Crisis?
- Moderator: Christine L H Snozek
- Experts: Leland B Baskin, Jessica M Boyd, Brian N Kelly, Matthew D Krasowski, S M Hossein Sadrzadeh, Danyel H Tacker
- DOI: https://doi.org/10.1093/clinchem/hvaa305
The Dynamic and Multifaceted Nature of Cardiovascular Disease and Using Genetic Testing to Inform Clinical Care: An International Perspective
- Moderator: Linnea M Baudhuin
- Experts: Julie De Backer, Jodie Ingles, Dianna M Milewicz, Anne Tybjaerg-Hansen
- DOI: https://doi.org/10.1093/clinchem/hvaa251
2020
Cell-Free DNA Fragmentomics: The New "Omics" on the Block
- Moderator: Rossa W.K. Chiu
- Experts: Ellen Heitzer, Y M Dennis Lo, Florent Mouliere, Dana W Y Tsui
- DOI: https://doi.org/10.1093/clinchem/hvaa258
Examining Laboratory Medicine's Role in Eliminating Health Disparities
- Moderator: Sarah E. Wheeler
- Experts: Octavia M Peck Palmer, Dina N Greene, Jason Y Park, Gabrielle Winston-McPherson, Timothy K Amukele, Eliseo J Pérez-Stable
- DOI: https://doi.org/10.1093/clinchem/hvaa174
Patient-Based Real Time QC
- Moderator: Tony Badrick
- Experts: Andreas Bietenbeck, Alex Katayev, Huub H van Rossum, Mark A Cervinski, Tze Ping Loh on behalf of the International Federation of Clinical Chemistry and Laboratory Medicine Committee on Analytical Quality
- DOI: https://doi.org/10.1093/clinchem/hvaa149
Challenges of High-Resolution Mass Spectrometry For Detecting Designer Drugs
- Moderator: Frederick G. Strathmann
- Experts: Kara L. Lynch, Alex Krotulski, Pierre Negri, Julie Cichelli, Markus R. Meyer
- DOI: https://doi.org/10.1093/clinchem/hvaa118
What is Extrachromosomal Circular DNA and What Does It Do?
- Moderator: Rossa W.K. Chiu
- Experts: Anindya Dutta, Anton G. Henssen, Y.M. Dennis Lo, Paul Mischel, Birgitte Regenberg
- DOI: https://doi.org/10.1093/clinchem/hvaa096
The SARS-CoV-2 Outbreak: Diagnosis, Infection Prevention, and Public Perception
- Moderators: Ping Wang, Neil Anderson
- Experts: Yang Pan, Leo Poon, Carmen Charlton, Nathan Zelyas, David Persing, Daniel Rhoads, Hilary Babcock
- DOI: https://doi.org/10.1093/clinchem/hvaa080
Fecal Microbiota Transplantations: Where Are We, Where Are We Going, And What is the Role of the Clinical Laboratory?
- Moderators: Eric M. Ransom, Carey-Ann Burnham
- Experts: Lee Jones, Colleen S. Kraft, L. Clifford McDonald, Andrew R. Reinink, Vincent B. Young
- DOI: https://doi.org/10.1093/clinchem/hvaa021
Development, Validation, and Regulatory Considerations for a Liquid Biopsy Test
- Moderators: Dana W.Y. Tsui, Gideon M. Bluementhal, Reena Philip
- Experts: J. Carl Barrett, Clara Montagut, Kelli Bramlett, Marc Ladanyi, Soma Ghosh
- DOI: 10.1373/clinchem.2019.305169
Use of Biomarkers to Detect and Manage Acute Kidney Injury: Has Progress Stalled?
- Moderator: John C. Lieske
- Experts: Kianoush Kashani, John Kellum, Jay Koyner, Ravindra Mehta, Chirag R. Parikh
- DOI: https://doi.org/10.1093/clinchem/hvz026
Predictive and Precision Medicine with Genomic Data
- Moderator: Linnea M. Baudhuin
- Experts: Leslie G. Biesecker, Wylie Burke, Eric D. Green, Robert C. Green
- DOI: 10.1373/clinchem.2019.304345
2019
Perspectives on the Changing Landscape of Measuring Cardiovascular Risk Related to LDL
- Moderators: Joe M. El-Khoury, Alan T. Remaley
- Experts: Børge G. Nordestgaard, Harvey W. Kaufman, Samia Mora, Jing Cao, Jeffrey W. Meeusen
- DOI: 10.1373/clinchem.2019.307306
Machine Learning for Clinical Chemists
- Moderator: Tony Badrick
- Experts: Giuseppe Banfi, Andreas Bietenbeck, Mark A. Cervinski, Tze Ping Loh, Ken Sikaris
- DOI: 10.1373/clinchem.2019.307512
Challenges Facing Society Journals
- Moderator: Thomas Annesley
- Experts: Kent Anderson, Angela Cochran, David Crotty, Richard Gallagher, Lisa Janicke Hinchliffe
- DOI: 10.1373/clinchem.2019.310268
Role of BNP vs NT-proBNP Testing in the Age of New Drug Therapies: Sacubitril-Valsartan
- Moderator: Fred S. Apple
- Experts: Lori B. Daniels, James Januzzi, Torbjørn Omland, Jordi Ordonez-Llanos, Allan Jaffe
- DOI: 10.1373/clinchem.2018.28937
Optimal Use of Biomarkers for Chronic Kidney Disease
- Moderator: W.Greg Miller
- Experts: Lorin M. Bachmann, Joris R. Delanghe, Lesley A. Inker, Graham R.D. Jones, Joseph A. Vassalotti
- DOI: 10.1373/clinchem.2018.299073
Biobanking for Metabolomics and Lipidomics in Precision Medicine
- Moderator: Jennifer A. Kirwan
- Experts: Rima Kaddurah-Daouk, Todd Mitchell, Tobias Pischon, Michael A. Schmidt, Vidya Velagapudi
- DOI: 10.1373/clinchem.2018.298620
What the Protecting Access to Medicare Act Means for Clinical Laboratories
- Moderators: James H. Nichols, Vincent G. Stine
- Experts: Rodney W. Forsman, Lee H. Hilborne, Elissa B. Passiment, Paul Radensky, Charles B. Root, Ester Stein
- DOI: 10.1373/clinchem.2019.303255
Privacy in Direct-to-Consumer Genetic Testing
- Moderator: Jason Y. Park
- Experts: Michael T. Risher, Timothy Caulfield, Linnea M. Baudhuin, Abraham P. Schwab
- DOI: 10.1373/clinchem.2018.298935
Mass Spectrometry-Based Tissue Imaging: The Next Frontier in Clinical Diagnostics?
- Moderators: Felix Leung, Livia S. Eberlin
- Experts: Kristina Schwamborn, Ron M.A. Heeren, Nicholas Winograd, R. Graham Cooks
- DOI: 10.1373/clinchem.2018.289694
Challenges in the Assessment and Diagnosis of Polycystic Ovary Syndrome
- Moderator: Joseph R. Wiencek
- Experts: Christopher R. McCartney, Alice Y. Chang, Joely A. Straseski, Richard J. Auchus, Alison Woodworth
- DOI: 10.1373/clinchem.2017.284331
Maintaining Research and Publication Integrity
- Moderators: Nader Rifai, Thomas M. Annesley
- Experts: Scott Moore, Arthur L. Caplan, Deborah J. Sweet, Peter Hornung, Frits R. Rosendaal
- DOI: 10.1373/clinchem.2018.298901
The Microbiome and Men's Health
- Moderator: Elizabeth A. Platz
- Experts: Cindy M. Liu, Dominique S. Michaud, Noel T. Mueller, Jacques Ravel
- DOI: 10.1373/clinchem.2018.287284
2018
Updates on Screening, Prevention, Treatment, and Genetic Markers for Preeclampsia
- Moderator: Glenn E. Palomaki
- Experts: James N. Martin, S. Ananth Karumanchi, Liona C. Poon
- DOI: 10.1373/clinchem.2018.289801
Influence of Molecular Testing on Influenza Diagnosis
- Moderators: Melanie L. Yarbrough, Carey-Ann D. Burnham
- Experts: Neil W. Anderson, Ritu Banerjee, Christine C. Ginocchio, Kimberly E. Hanson, Timothy M. Uyeki
- DOI: 10.1373/clinchem.2018.289363
Learning in the 21st Century: Concepts and Tools
- Moderator: Nader Rifai
- Experts: Todd Rose, Graham T. McMahon, Bror Saxberg, Ulrik Juul Christensen
- DOI: 10.1373/clinchem.2018.292383
The Power of Social Media in Medicine and Medical Education: Opportunities, Risks, and Rewards
- Moderator: Amy K. Saenger
- Experts: Michael Berkwits, Simon Carley, Shannon Haymond, Marie Ennis-O'Connor, Jonathan Sherbino, Stephen W. Smith
- DOI: 10.1373/clinchem.2018.288225
There's No Place Like Home: Exploring Home-Based, Acute-Level Healthcare
- Moderators: Michelle L. Parker, Paul M. Yip
- Experts: Linda V. DeCherrie, Christian Escobar, Anna K. Fuezery, Christopher P. Price, Andrew St. John
- DOI: 10.1373/clinchem.2017.283093
What's New in Laboratory Test Utilization Management?
- Moderator: Geoffrey S. Baird
- Experts: Brian R. Jackson, Jane Dickerson, Ken Sikaris, Bernard Croal, Michael Laposata
- DOI: 10.1373/clinchem.2017.280214
Current and Emerging Multianalyte Assays with Algorithmic Analyses—Are Laboratories Ready for Clinical Adoption?
- Moderators: Jessica M. Colón-Franco, Patrick M.M. Bossuyt
- Experts: Alicia Algeciras-Schimnich, Christopher Bird, Julia Engstrom-Melnyk, Martin Fleisher, Michael Kattan, Geralyn Lambert-Messerlian
- DOI: 10.1373/clinchem.2017.275677
Debates in Pain Management Testing
- Moderator: Stacy E.F. Melanson
- Experts: William A. Clarke, Keith Fragoza, Christopher Gilligan, Rebecca Holdren, Paul J. Jannetto, Barbarajean Magnani, Christine Moore
- DOI: 10.1373/clinchem.2017.275693
A Q&A with the Qualcomm Tricorder XPRIZE Winners
- Moderators: Ann M. Gronowski, Shannon Haymond
- Experts: Basil Harris, Chung Kang Peng, Sandeep (Sonny) S. Kohli
- DOI: 10.1373/clinchem.2017.278853
Gestational Diabetes Mellitus: Why the Controversy?
- Moderator: David B. Sacks
- Experts: Donald R. Coustan, Tim Cundy, Lois Donovan, Moshe Hod
- DOI: 10.1373/clinchem.2016.266577
Challenges and Opportunities in Implementing Total Laboratory Automation
- Moderator: Jonathan R. Genzen
- Experts: Carey-Ann D. Burnham, Robin A. Felder, Charles D. Hawker, Giuseppe Lippi, Octavia M. Peck Palmer
- DOI: 10.1373/clinchem.2017.274068
Dietary Fat: Friend or Foe?
- Moderators: Cara B. Ebbeling, Ian S. Young
- Experts: Alice H. Lichtenstein, David S. Ludwig, Michelle McKinley, Rafael Perez-Escamilla, Eric Rimm
- DOI: 10.1373/clinchem.2017.274084
2017
New Therapies for Treating Hepatitis C Virus: Impact on Laboratory Testing Recommendations and Clinical Management
- Moderators: Nicole V. Tolan, Gary L. Horowitz
- Experts: Joel Dore, Francisco Guarner, Ruth Ann Luna, Yehuda Ringel
- DOI: 10.1373/clinchem.2016.266569
Microbiome-Based Diagnostics: Ready for Applications in Laboratory Medicine?
- Moderator: James Versalovic
- Experts: Camilla S. Graham, David Hillyard, William Osburn, Stuart Ray
- DOI: 10.1373/clinchem.2016.264473
Impact of Novel Psychoactive Substances on Clinical and Forensic Toxicology and Global Public Health
- Moderator: Marilyn A. Huestis
- Simon D. Brandt, Suman Rana, Volker Auwärter, Michael H. Baumann
- DOI: 10.1373/clinchem.2017.274662
The Role of Procalcitonin in Diagnosis of Sepsis and Antibiotic Stewardship: Opportunities and Challenges
- Moderators: Angela W.S. Fung, Daniel Beriault, Eleftherios P. Diamandis
- Experts: Carey-Ann D. Burnham, Todd Dorman, Mark Downing, Joshua Hayden, Bradley J. Langford
- DOI: 10.1373/clinchem.2017.272294
Patient Privacy and Clinical Laboratory Data
- Moderator: Jason Y. Park
- Experts: Toby C. Cornish, Michael Hogarth, Brian R. Jackson, Kristen B. Rosati
- DOI: 10.1373/clinchem.2016.266551
The Phoenix Rises: The Rebirth of Cancer Immunotherapy
- Moderators: Ivan M. Blasutig, Sofia Farkona
- Experts: Elizabeth I. Buchbinder, Jason J. Luke, Padmanee Sharma, Mario Sznol
- DOI: 10.1373/clinchem.2016.267849
Wellness Initiatives: Benefits and Limitations
- Moderators: Michelle Li, Eleftherios P. Diamandis
- Experts: Nigel Paneth, Kiang-Teck J. Yeo, Henrik Vogt, Stephen R. Master
- DOI: 10.1373/clinchem.2017.273672
Emerging Considerations for Noninvasive Prenatal Testing
- Moderators: Nichole Korpi-Steiner, Rossa W.K. Chiu
- Experts: Subhashini Chandrasekharan, Lyn S. Chitty, Mark I. Evans, Judith A. Jackson, Glenn E. Palomaki
- DOI: 10.1373/clinchem.2016.266544
Are We There Yet? Laboratory Preparedness for Emerging Infectious Diseases
- Moderators: Carey-Ann D. Burnham, Jennie H. Kwon
- Experts: Eileen M. Burd, Sheldon Campbell, Peter C. Iwen, Melissa B. Miller
- DOI: 10.1373/clinchem.2016.265850
Direct-to-Consumer Testing
- Moderators: Michelle Li, Eleftherios P. Diamandis
- Experts: David Grenache, Michael J. Joyner, Daniel T. Holmes, Rodger Seccombe
- DOI: 10.1373/clinchem.2016.260349
Biomedical Journals and Preprint Services: Friends or Foes?
- Moderators: Thomas Annesley, Mitchell Scott
- Experts: Hilda Bastian, Vivian Fonseca, John P.A. Ioannidis, Michael A. Keller, Jessica Polka
- DOI: 10.1373/clinchem.2016.268227
Best Practices for Monitoring Cardiac Troponin in Detecting Myocardial Injury
- Moderator: Fred S. Apple
- Experts: Allan S. Jaffe, Scott Sharkey, Peter Kavsak, Michael C. Kontos, Amy K. Saenger, Stephen Smith
- DOI: 10.1373/clinchem.2016.257428
2016
The Use of Targeted Therapies for Precision Medicine in Oncology
- Moderators: Nicole White-Al Habeeb, Vathany Kulasingam, and Eleftherios P. Diamandis
- Experts: George M. Yousef, Gregory J. Tsongalis, Louis Vermeulen, Ziqiang Zhu, and Suzanne Kamel-Reid
- DOI: 10.1373/clinchem.2015.247882
Newborn Screening for Lysosomal Storage Disorders: Quo Vadis?
- Moderators: Roy W.A. Peake and Deborah L. Marsden
- Experts: Olaf A. Bodamer, Michael H. Gelb, David S. Millington and Frits Wijburg
- DOI: 10.1373/clinchem.2016.258459
CRISPR-Cas9 System: Opportunities and Concerns
- Moderators: Stella Vasiliou and Eleftherios P Diamandis
- Experts: George Church, Henry T Greely, Françoise Baylis, Charis Thompson, and Gerold Schmitt‐Ulms
- DOI: 10.1373/clinchem.2016.263186
Zika Virus: From Obscurity to Potentially Devastating International Threat
- Moderators: Marie Louise Landry
- Experts: Albert I. Ko, Laura D. Kramer and Nikolaos Vasilakis
- DOI: 10.1373/clinchem.2016.261917
Circulating Tumor DNA as a Cancer Biomarker: Fact or Fiction?
- Moderators: Felix Leung, Vathany Kulasingam, and Eleftherios P. Diamandis
- Experts: Dave S. B. Hoon, Kenneth Kinzler, Klaus Pantel, and Catherine Alix- Panabières
- DOI: 10.1373/clinchem.2016.260331
Reference Intervals: Strengths, Weaknesses, and Challenges
- Moderators: W. Greg Miller and Gary L. Horowitz
- Experts: Ferruccio Ceriotti, James K. Fleming, Neil Greenberg, Alexander Katayev, Graham R.D. Jones, William Rosner, and Ian S. Young
- DOI: 10.1373/clinchem.2016.256511
Classifying Germline Sequence Variants in the Era of Next-Generation Sequencing
- Moderators: Linnea M. Baudhuin and Birgit H. Funke
- Experts: Lora H. Bean, Joshua L. Deignan, Sean Hofherr, David T. Miller, Narasimhan Nagan, Avni Santani, and Carol Saunders
- DOI: 10.1373/clinchem.2015.247874
Pharmacists in the Laboratory Space: Friends or Foes?
- Moderator: Ann M. Gronowski
- Experts: Alex Adams, Christopher Ball, Charlotte A. Gaydos, and Michael Klepser
- DOI: 10.1373/clinchem.2015.247445
Proteogenomics: Opportunities and Caveats
- Moderators: Lampros Dimitrakopoulos, Ioannis Prassas, and Eleftherios P. Diamandis
- Experts: Alexey Nesvizhskii, Thomas Kislinger, Jacob Jaffe, and Andrei Drabovich
- DOI: 10.1373/clinchem.2015.247858
Nonfasting Sample for the Determination of Routine Lipid Profile: Is It an Idea Whose Time Has Come?
- Moderators: Nader Rifai and Ian S. Young
- Experts: Børge G. Nordestgaard, Anthony S. Wierzbicki, Hubert Vesper, Samia Mora, Neil J. Stone, Jacques Genest, and Greg Miller
- DOI: 10.1373/clinchem.2015.247866
Clostridium difficile—Diagnostic and Clinical Challenges
- Moderator: Carey-Ann D. Burnham
- Experts: Erik R. Dubberke, Larry K. Kociolek, Christopher R. Polage, and Thomas V. Riley
- DOI: 10.1373/clinchem.2015.243717
A Spectrum of Views on Clinical Mass Spectrometry
- Moderators: Thomas Annesley and Eleftherios Diamandis
- Experts: Lorin Bachmann, Samir Hanash, Bradley Hart, Reza Javahery, Ravinder Singh, and Richard Smith
- DOI: 10.1373/clinchem.2015.250258
2015
Vitamin D: The More We Know, the Less We Know
- Moderators: Mitchell G. Scott and Ann M. Gronowski
- Experts: Ian R. Reid, Michael F. Holick, Ravi Thadhani, and Karen Phinney
- DOI: 10.1373/clinchem.2014.222521
Biomarkers in the Pharmaceutical Industry
- Moderator: Omar F. Laterza
- Experts: Andrew Plump, Jeffrey E. Ming, Susan Richards, Michael E. (Ransom) Burczynski, John A. Wagner, and Scott D. Patterson
- DOI: 10.1373/clinchem.2014.225284
"Big Data" in Laboratory Medicine
-
Moderators: Nicole V. Tolan and M. Laura Parnas
- Experts: Linnea M. Baudhuin, Mark A. Cervinski, Albert S. Chan, Daniel T. Holmes, Gary Horowitz, Eric W. Klee, Rajiv B. Kumar, and Stephen R. Master
- DOI: 10.1373/clinchem.2015.248591
Triangulating Dynamic of Clinical Laboratory Testing
- Moderators: Kerri Weinert, Peter Gyorda, and Nader Rifai
- Experts: Susan Evans, Harvey W. Kaufman, Charles S. Eby, Edward R. Ashwood, and Norman Moore
- DOI: 10.1373/clinchem.2015.248112
Clopidogrel and CYP2C19: PharmacogeneticTesting Ready for Clinical Prime Time?
- Moderators: Michael J. Knauer and Eleftherios P. Diamandis
- Experts: Jean-Sebastien Hulot, Richard B. Kim, and Derek Y.F. So
- DOI: 10.1373/clinchem.2015.238105
Disruptive Innovation in Laboratory Medicine
-
Moderator: Nader Rifai
- Experts: Eric Topol, Eugene Chan, Y.M. Dennis Lo, and Carl T. Wittwer
- DOI: 10.1373/clinchem.2015.243667
A Renin-ssance in Primary Aldosteronism Testing: Obstacles and Opportunities for Screening, Diagnosis, and Management
- Moderators: Joshua E. Raizman and Eleftherios P. Diamandis
- Experts: Daniel Holmes, Michael Stowasser, Richard Auchus, and Etienne Cavalier
- DOI: 10.1373/clinchem.2015.242990
Biomarkers, Assays, and Therapies for Alzheimer Disease
- Moderators: Daniel R. Beriault and Eleftherios P. Diamandis
- Experts: Erik Portelius, Armand Perret-Liaudet, and Stephen Salloway
- DOI: 10.1373/clinchem.2015.241901
Preanalytical Considerations in the Design of Clinical Trials and Epidemiological Studies
- Moderator: Mark D. Kellogg
- Experts: Christina Ellervik, David Morrow, Ann Hsing, Evan Stein, and Amar A. Sethi
- DOI: 10.1373/clinchem.2014.226118
Preeclampsia: An Old Disease with New Tools for Better Diagnosis and Risk Management
- Moderators: Mohamed Abou El Hassan and Eleftherios P. Diamandis
- Experts: S. Ananth Karumanchi, Andrew H. Shennan, and Robert N. Taylor
- DOI: 10.1373/clinchem.2014.230565
The Changing Face of Laboratory Medicine: A More Service and Less Academically Oriented Profession?
- Moderators: Mitchell G. Scott and Nader Rifai
- Experts: Brian Smith, Michael Oellerich, Mauro Panteghini, Fred Apple, Ken Sikaris, and Ian Young
- DOI: 10.1373/clinchem.2014.230300
Next Generation Sequencing in Clinical Diagnostics: Experiences of Early Adopters
- Moderator: Elaine Lyon, Franklin R. Cockerill III
- Richard Press, and Glenn E. Palomaki
- DOI: 10.1373/clinchem.2014.222687
2014
Animal Olfactory Detection of Disease: Promises and Pitfalls
- Moderators: Tracy Teodoro-Morrison, Eleftherios P. Diamandis, and Nader Rifai
- Experts: Bart Jan Christiane Weetjens, Giorgio Pennazza, Nanne K. de Boer, and Marije K. Bomers
- DOI: 10.1373/clinchem.2014.231282
Critical Issues in International Biobanking
- Moderator: Jim Vaught
- Experts: Akin Abayomi, Tim Peakman, Peter Watson, Lise Matzke, and Helen Moore
- DOI: 10.1373/clinchem.2014.224469
What Is Wrong with Clinical Proteomics?
- Moderators: Ashley Di Meo and Eleftherios P. Diamandis
- Experts: Henry Rodriguez, Andrew N. Hoofnagle, John Ioannidis, and Mary Lopez
- DOI: 10.1373/clinchem.2014.225185
Registering Diagnostic and Prognostic Trials of Tests: Is It the Right Thing to Do?
- Moderators: Nader Rifai and Patrick M.M. Bossuyt
- Experts: John P.A. Ioannidis, Kurtis R. Bray, Lisa M. McShane, Robert M. Golub, and Lotty Hooft
- DOI: 10.1373/clinchem.2014.226100
Natriuretic Peptides in Heart Failure
- Moderators: Danny C.C. Lin and Eleftherios P. Diamandis
- Experts: James L. Januzzi Jr., Alan Maisel, Allan S. Jaffe, and Aldo Clerico
- DOI: 10.1373/clinchem.2014.223057
Harmonization of Test Results: What Are the Challenges; How Can We Make It Better?
- Moderator: W. Greg Miller
- Experts: John H. Eckfeldt, Joseph Passarelli, William Rosner, and Ian S. Young
- DOI: 10.1373/clinchem.2012.201186
Novel Biomarkers for Acute Myocardial Infarction: Is MicroRNA the New Kid on the Block?
- Moderators: Joshua E. Raizman and Eleftherios P. Diamandis
- Experts: Katey Rayner, Stephanie Dimmeler, George A. Calin, and Thomas Thum
- DOI: 10.1373/clinchem.2013.215491
Interferon γ–Release Assays for Diagnosis of Latent Tuberculosis in Healthcare Workers in Low-Incidence Settings: Pros and Cons
- Moderators: Nira R. Pollock and Alexander J. McAdam
- Experts: Madhukar Pai, Edward A. Nardell, John Bernardo, Niaz Banaei, and Jay Mobo
- DOI: 10.1373/clinchem.2012.201178
Helicobacter pylori Diagnostics and Treatment: Could a Lack of Universal Consensus Be the Best Consensus?
- Moderator: Marc R. Couturier
- Experts: Barry J. Marshall, Karen J. Goodman, and Francis Mégraud
- DOI: 10.1373/clinchem.2012.201475
Novel Uses for Platelet Function Testing in the Clinical Laboratory: Where Are We Now?
- Moderator: Brad S. Karon
- Experts: Gilles Montalescot, Neil S. Harris, Søren Risom Kristensen, and Matthew Price
- DOI: 10.1373/clinchem.2013.208942
Biomarkers for Acute Kidney Injury: Where Are We Today? Where Should We Go?
- Moderator: John C. Lieske
- Experts: Lakhmir Chawla, Kianoush Kashani, John A. Kellum, Jr., Jay L. Koyner, and Ravindra L. Mehta
- DOI: 10.1373/clinchem.2012.201988
The Ethical Implications of Preimplantation Genetic Diagnosis
- Moderator: Ann M. Gronowski
- Experts: Richard T. Scott, Jr., Arthur L. Caplan, and Lawrence J. Nelson
- DOI: 10.1373/clinchem.2013.202515
2013
Automation in the Clinical Microbiology Laboratory
- Moderator: Carey-Ann D. Burnham
- Experts: W. Michael Dunne, Jr., Gilbert Greub, Susan M. Novak, and Robin Patel
- DOI: 10.1373/clinchem.2012.201038
Identifying Antibiotic-Resistant Bacteria in Hospitalized Patients: What Is the Role of Active-Surveillance Cultures?
- Moderator: Thomas J. Sandora
- Experts: Susan A. Dolan, Stephan Harbarth, Susan S. Huang, Alexander J. McAdam, and Aaron M. Milstone
- DOI: 10.1373/clinchem.2012.201046
Use of MALDI-TOF for Diagnosis of Microbial Infections
- Moderators: Dana Bailey and Eleftherios P. Diamandis
- Experts: Gilbert Greub, Susan M. Poutanen, Jens Jørgen Christensen, and Markus Kostrzew
- DOI: 10.1373/clinchem.2013.204644
Bioinformatics: What the Clinical Laboratorian Needs to Know and Prepare For
- Moderator: Gregory J. Tsongalis
- Experts: Elizabeth Chao, Jill M. Hagenkord, Tina Hambuch, and Jason H. Moore
- DOI: 10.1373/clinchem.2012.198226
A New Era in Prenatal Diagnosis: The Use of Cell-Free Fetal DNA in Maternal Circulation for Detection of Chromosomal Aneuploidies
- Moderators: Jennifer L. Shea and Eleftherios P. Diamandis
- Experts: Barry Hoffman, Y.M. Dennis Lo, Jacob Canick, and Dirk van den Boom
- DOI: 10.1373/clinchem.2012.201996
FDA Oversight of Laboratory-Developed Tests: Is It Necessary, and How Would It Impact Clinical Laboratories?
- Moderator: Mitchell G. Scott
- Experts: Edward R. Ashwood, Thomas M. Annesley, Debra G.B. Leonard, and Michael C. Burgess
- DOI: 10.1373/clinchem.2013.204958
Cobalt and Chromium Measurement in Patients with Metal Hip Prostheses
- Moderators: Mathew P. Estey and Eleftherios P. Diamandis
- Experts: Catherine Van Der Straeten, Stephen S. Tower, Alister J. Hart, and Thomas P. Moyer
- DOI: 10.1373/clinchem.2012.193037
Iron Deficiency: What Are the Future Trends in Diagnostics and Therapeutics?
- Moderator: Carlo Brugnara
- Experts: John Adamson, Michael Auerbach, Robert Kane, Iain Macdougall, and Alan Mast
- DOI: 10.1373/clinchem.2012.182071
Communication of Scientific Information: Is It Time to Reassess?
- Moderators: Nader Rifai and John Sack
- Experts: Michael A. Keller, Anurag Acharya, Philip E. Bourne, Mike Rossner, and Stewart Wills
- DOI: 10.1373/clinchem.2012.194738
Pheochromocytoma
- Moderators: Mathew P. Estey and Eleftherios P. Diamandis
- Experts: Graeme Eisenhofer, Karel Pacak, Eamonn R. Maher, William F. Young, and Ronald R. de Krijger
- DOI: 10.1373/clinchem.2012.182246
MicroRNA Analysis: Is It Ready for Prime Time?
- Moderator: Gregory J. Tsongalis
- Experts: George Calin, Pierre Cordelier, Carlo Croce, Federico Monzon, and Anna E. Szafranska-Schwarzbach
- DOI: 10.1373/clinchem.2012.185009
Pancreatic Cancer
- Moderators: Caitlin C. Chrystoja and Eleftherios P. Diamandis
- Experts: Randall Brand, Felix Rückert, Randy Haun, and Rafael Molina
- DOI: 10.1373/clinchem.2012.196642
2012
NHLBI Integrated Guidelines on Cardiovascular Disease Risk Reduction: Can We Clarify the Controversy about Cholesterol Screening and Treatment in Childhood?
- Moderator: Sarah D. de Ferranti
- Experts: Stephen R. Daniels, Matthew Gillman, Louis Vernacchio, Jorge Plutzky, and Annette L. Baker
- DOI: 10.1373/clinchem.2012.182089
Autoimmune Diseases: Early Diagnosis and New Treatment Strategies
- Moderators: Danijela Konforte and Eleftherios P. Diamandis
- Experts: Walther J. van Venrooij, Rik Lories, and Michael M. Ward
- DOI: 10.1373/clinchem.2012.189480
Thyroid Function during Pregnancy: Who and How Should We Screen?
- Moderator: Ann M. Gronowski
- Experts: James Haddow, Sarah Kilpatrick, John H. Lazarus, and Roberto Negro
- DOI: 10.1373/clinchem.2012.185017
Ectopic Pregnancy
- Moderators: Julie L.V. Shaw and Eleftherios P. Diamandis
- Experts: Andrew Horne, Kurt Barnhart, Tom Bourne, and Ioannis E. Messinis
- DOI: 10.1373/clinchem.2012.184168
Antibiotic Resistance: How Serious Is the Problem, and What Can Be Done?
- Moderators: Alexander J. McAdam
- Experts: David C. Hooper, Alfred DeMaria, Brandi M. Limbago, Thomas F. O'Brien, and Betsy McCaughey
- DOI: 10.1373/clinchem.2011.181636
Altering the Landscape for Women in Clinical Chemistry: Perspectives from Multigenerational Leaders
- Moderators: Shannon Haymond and Amy K. Saenger
- Experts: Helen M. Free, Jocelyn M. Hicks, Marilyn A. Huestis, Rita Horvath, and Corinne R. Fantz
- DOI: 10.1373/clinchem.2011.174284
The Obesity Epidemic
- Moderators: Jennifer Shea and Eleftherios P. Diamandis
- Experts: Arya M. Sharma, Jean-Pierre Després, Shereen Ezzat, and Frank Greenway
- DOI: 10.1373/clinchem.2011.180976
Liquid Chromatography-Tandem Mass Spectrometry or Automated Immunoassays: What Are the Future Trends in Therapeutic Drug Monitoring?
- Moderators: Gunnar Brandhorst and Michael Oellerich
- Experts: Gregory Maine, Paul Taylor, Gerhard Veen, and Pierre Wallemacq
- DOI: 10.1373/clinchem.2011.167189
Is Leadership a Noun or Verb?
- Moderator: Thomas M. Annesley
- Experts: James S. Hernandez, Angie Morgan, Ora Pescovitz, and Ian Wright
- DOI: 10.1373/clinchem.2011.165639
How Well Are We Training the Next Generation of Clinical Pathologists and Clinical Laboratory Directors? A Global Perspective
- Moderator: Mitchell G. Scott
- Experts: Brian R. Smith, Alan H.B. Wu, Ian S. Young, Mario Plebani, and Rossa W.K. Chiu
- DOI: 10.1373/clinchem.2011.171199
Newborn Screening for Metabolic Disorders: How Are We Doing, and Where Are We Going?
- Moderator: Michael J. Bennett
- Experts: Piero Rinaldo, Bridget Wilcken, Kenneth A. Pass, Michael S. Watson, and Ronald J.A. Wanders
- DOI: 10.1373/clinchem.2011.171215
The Challenges and Concerns Companies Face Pertaining to the US Food and Drug Administration 510(k) Process for Cardiac Biomarkers
- Moderators: Fred S. Apple and David Morrow
- Experts: Christian Zaugg, David Hickey, Michelle Zaharik, John J. Blackwood, and Kirsten Jakobsen
- DOI: 10.1373/clinchem.2011.165860
2011
Painting a Moving Picture: Large-Scale Proteomics Efforts and Their Potential for Changing Patient Care
- Moderator: Andrew Hoofnagle
- Experts: Ruedi Aebersold, N. Leigh Anderson, Adam Felsenfeld, and Daniel C. Liebler
- DOI: 10.1373/clinchem.2010.158311
Invest or Not to Invest ... Not Always an Easy Question to Answer
- Moderator: Susan Evans
- Experts: Emery Stephans, Avi Kulkarni, Aaron Geist and Quintin Lai
- DOI: 10.1373/clinchem.2010.152132
Direct-to-Consumer Genetic Testing: Reliable or Risky?
- Moderators: David H. Spencer and Christina Lockwood
- Experts: Eric Topol, James P. Evans, Robert C. Green, Elizabeth Mansfield, and Zivana Tezak
- DOI: 10.1373/clinchem.2011.167197
Circulating Cancer Cells and Their Clinical Applications
- Moderator: Eleftherios P. Diamandis
- Experts: Klaus Pantel, Howard I. Scher, Leon Terstappen, and Evi Lianidou
- DOI: 10.1373/clinchem.2011.166678
Painting a Moving Picture: Large-Scale Proteomics Efforts and Their Potential for Changing Patient Care
- Moderator: Andrew N. Hoofnagle
- Experts: Ruedi Aebersold, N. Leigh Anderson, Adam Felsenfeld, and Daniel C. Liebler
- DOI: 10.1373/clinchem.2010.158311
Clinical Applications for Vitamin D Assays: What Is Known and What Is Wished for
- Moderator: Michael Kleerekoper
- Experts: Rosemary L. Schleicher, John Eisman, Roger Bouillon, Ravinder J. Singh and Michael F. Holick
- DOI: 10.1373/clinchem.2010.154997
Oral Fluid Testing: Promises and Pitfalls
- Moderator: Marilyn A. Huestis
- Experts: Alain Verstraete, Tai C. Kwong, Jorg Morland, Michael J. Vincent, and Raphael de la Torre
- DOI: 10.1373/clinchem.2010.152124
Alzheimer Disease: Advances in Pathogenesis, Diagnosis, and Therapy
- Moderators: Maria Diamandis Pasic and Eleftherios P. Diamandis
- Experts: JoAnne McLaurin, David M. Holtzman, Gerold Schmitt-Ulms, and Rémi Quirion
- DOI: 10.1373/clinchem.2011.161828
Individually Tailored Immunosuppression: Is There a Role for Biomarkers?
- Moderators: Gunnar Brandhorst and Michael Oellerich
- Experts: ;Mercè Brunet, Richard Kowalski, Alexander Vinks and Pierre Wallemacq
- DOI: 10.1373/clinchem.2010.159871
The Quest for Clean Competition in Sports: Are the Testers Catching the Dopers?
- Moderator: Anthony W. Butch
- Experts: John A. Lombardo, Larry D. Bowers, Julie Chu and David A. Cowan
- DOI: 10.1373/clinchem.2010.155002
The Use of Human Tissues in Research: What Do We Owe the Research Subjects?
- Moderator: Ann M. Gronowski
- Experts: Jack Moye, Jr., David S. Wendler, Arthur L. Caplan and Michael Christman
- DOI: 10.1373/clinchem.2010.154989
2010
Cancer Genomes
- Moderator: Eleftherios P. Diamandis
- Experts: Thomas Hudson, Olli Kallioniemi, Edison T. Liu and Carlos López-Otín
- DOI: 10.1373/clinchem.2010.152140
Nanotechnology: Improving Clinical Testing?
- Moderators: Paolo Fortina and Larry J. Kricka
- Experts: Dawn Bonnell, Amit Kulkarni, Joseph Wang, Yuri Miyahara, and David Ure
- DOI: 10.1373/clinchem.2009.138750
Epigenomics-Based Diagnostics
- Moderator: Eleftherios P. Diamandis
- Experts: David Sidransky, Peter W. Laird, Paul Cairns and Bharati Bapat
- DOI: 10.1373/clinchem.2010.148007
Direct-to-Consumer Genotyping: Are We Ready for a Brave New World?
- Moderators: Mark A. Cervinski and Gregory J. Tsongalis
- Experts: Lew Bender, Lawrence M. Silverman, Mary Bet Dinulos, Jim Nickel and Wayne Grody
- DOI: 10.1373/clinchem.2009.138743
High-Sensitivity Cardiac Troponin Assays: What Analytical and Clinical Issues Need to Be Addressed before Introduction into Clinical Practice?
- Moderator: Fred S. Apple
- Experts: Alan Wu, Paul Collinson, Allan Jaffe and David Morrow
- DOI: 10.1373/clinchem.2009.138727
KRAS Mutation Detection: A New Look at an Old Gene
- Moderators: Joel A. Lefferts and Gregory J. Tsongalis
- Experts: Arief A. Suriawinata, William K. Funkhouser, Marc Ladanyi, Jan A. Nowak and J. Marc Pipas
- DOI: 10.1373/clinchem.2009.138735
Microtechnology in the Clinical Laboratory: Will It Solve Analytical Problems, and When Will It Make an Impact?
- Moderator: Peter Wilding
- Experts: Sabeth Verpoorte, M. Allen Northrup, Paul Yager, Stephen Quake and James Landers
- DOI: 10.1373/clinchem.2009.138719
Prostate Cancer Screening with Prostate-Specific Antigen Testing: More Answers or More Confusion?
- Moderator: Eleftherios P. Diamandis
- Experts: Patrick Walsh, Klaus Jung, William Catalona and Neil Fleshner
- DOI: 10.1373/clinchem.2009.140046
Detection of Biological Agents Used for Terrorism: Are We Ready?
- Moderator: Mark Kellogg
- Experts: Mark Hollis, Cheryl Gauthier, and Tom O'Brien
- DOI: 10.1373/clinchem.2009.139493
2009
Next-Generation Sequencing: A New Revolution in Molecular Diagnostics?
- Moderator: Eleftherios P. Diamandis
- Experts: Karl V. Voelkerding, Rade Drmanac, David Agus, and John McPherson
- DOI: 10.1373/clinchem.2009.133389
Clinical Assays for Human Chorionic Gonadotropin: What Should We Measure and How?
- Moderator: Ann M. Gronowski
- Experts: Catherine Sturgeon, Ulf-Håkan Stenman, Glenn D. Braunstein, Anthony W. Butch and David A. Cowan
- DOI: 10.1373/clinchem.2009.133595
Tight Glucose Control in Critically Ill Patients: Should Glucose Meters Be Used?
- Moderator: David B. Sacks
- Experts: Greet Van den Berghe, Sue Kirkman, Gerald Kost, Ron Ng and Sverre Sandberg
- DOI: 10.1373/clinchem.2009.131318
Protein Quantification by Mass Spectrometry: Is It Ready for Prime Time?
- Moderator: Eleftherios P. Diamandis
- Experts: Samir Hanash, Mary Lopez, Steven Carr, and Emanuel F. Petricoin III
- DOI: 10.1373/clinchem.2009.128058
Mass Spectrometry in the Clinical Laboratory: How Have We Done, and Where Do We Need to Be?
- Moderator: Thomas Annesley
- Experts: Joseph Majzoub, Ann Hsing, Alan Wu, Alan Rockwood and Donald Mason
- DOI: 10.1373/clinchem.2009.127522