Mass Spectrometry in the Clinical Lab: Best Practices and Current Applications

St. Louis, MO

October 9-10, 2014

Day 1
Thursday, October 9

SESSION I - Implementing Mass Spec Testing: Know Your Technologies

Basics of Mass Spectrometry in the Clinical Laboratory
Deborah French, PhD
University of California San Francisco (San Francisco, CA)
PDF Slides  PDF Handout

An Introduction to Liquid Chromatography
Brian A. Rappold
Essential Testing (Collinsville, IL)
PDF Slides  PDF Handout

Cleaning Up Your Sample Prep Processes
Julia C. Drees, PhD
Kaiser Permanente of Northern California (Berkeley, CA)
PDF Slides  PDF Handout

SESSION II – Part 1
LIFE CYCLE OF A MASS SPECTROMETRY ASSAY: Practical Considerations in Getting Your New Method Up and Running

Justification, Instrument Selection, Due Diligence, and Setting Up a Clinical Lab for Successful Implementation of MS
Robert L. Fitzgerald, PhD
University of California San Diego (San Diego, CA)
PDF Slides  PDF Handout

Considerations for Method Development and Method Validation
William A. Clarke, PhD, MBA
Johns Hopkins Hospital (Baltimore, MD)

SESSION II – PART 2
LIFE CYCLE OF A MASS SPECTROMETRY ASSAY: PRACTICAL CONSIDERATIONS for Method Validation and implementation

Post-Implementation Monitoring: Keeping Your LC-MS/MS Method on the Right Track
Julianne C. Botelho, PhD
Centers for Disease Control and Prevention (Atlanta, GA)
PDF Slides  PDF Handout

Applying Your Validated Methods in the Real World
James C. Ritchie, PhD
Emory University Hospital (Atlanta, GA)

SESSION II – PART 3
LIFE CYCLE OF A MASS SPECTROMETRY ASSAY: PRACTICAL CONSIDERATIONS for Maintaining the Test Process in a Real-Life Setting

Getting a Handle on Your Biggest Mass Spec Test Volumes
Russell P. Grant, PhD
LabCorp (Burlington, NC)
PDF Slides  PDF Handout

Putting IT All Together: Moving Data and Reporting Results
Judy A. Stone, PhD, MT(ASCP)
University of California at San Diego (San Diego, CA)
PDF Slides  PDF Handout

Day 2
Friday, October 10

SESSION III
SOME COMMON CURRENT APPLICATIONS

The Laboratory’s Role in Pain Management Testing
Frederick G. Strathmann, PhD
ARUP Laboratories (Salt Lake City, UT)
PDF Slides  PDF Handout

Delivering Accurate Adrenal and Sex Steroid Results with LC-MS/MS: Why Owning an Expensive Bicycle Doesn’t Make You a Good Cyclist
Daniel T. Holmes, MD
St. Paul’s Hospital Providence Health Care (Vancouver, British Columbia)
PDF Slides  PDF Handout

Mass Spectrometry in Babies and Beyond
Shannon M. Haymond, PhD
Lurie Children’s Hospital of Chicago (Chicago, IL)

SESSION IV
Industry Viewpoint

Applied Mass Spectrometry: Translational Research IVD
Sherry L. Gregory
Thermo Fisher Scientific (West Palm Beach, FL)
PDF Slides  PDF Handout

Topic TBD
Agilent Technologies

Implementation of Scalable Sample Preparation Workflow Solutions in a Clinical Laboratory
Frank A. Kero, PhD
Biotage
PDF Slides  PDF Handout

Topic TBD
Shimadzu Scientific Instruments

SESSION V
A Look to the Future

MALDI-TOF for Microbiology Applications
Susan Butler-Wu, PhD
University of Washington (Seattle, WA)

Using Mass Spectrometry to Measure Proteins in the Clinical Laboratory
Andrew N. Hoofnagle, MD, PhD
University of Washington (Seattle, WA)
PDF Slides