Mass Spectrometry in the Clinical Lab: Best Practices and Current Applications

Chicago, Illinois

ONLINE MANUAL

September 6, 2012

KEYNOTE PRESENTATION

Mass Spectrometry in the Clinical Laboratory
William A. Clarke, PhD
Johns Hopkins Hospital (Baltimore, MD)
(PDF slides) (PDF handouts)

SESSION I –Bringing up a New Mass Spec Method

CLSI C60: Method Development
Julianne C. Botelho, PhD
Centers for Disease Control and Prevention (Atlanta, GA)
(PDF slides) (PDF handouts)

CLSI C60: Method Validation & Post-Validation Monitoring
Ross J. Molinaro, PhD
Emory University Hospital (Atlanta, GA)
(PDF slides) (PDF handouts)

A Practical Example of C60 in Action: Vitamins and Hormones
Lorin M. Bachmann, PhD
VCU Health System (Richmond, VA)
(PDF slides) (PDF handouts)

Reference Materials and Traceability - Steps toward Harmonization
Mitzi M. Rettinger
Cerilliant Corp. (Round Rock, TX)
(PDF slides) (PDF handouts)

SESSION II – Mass Spectrometry Toolbox

Interactive Session: Common Method Errors and How to Fix Them
Russell P. Grant, PhD
LabCorp (Burlington, NC)
(PDF slides) (PDF handouts)

An Overview of Current Tools for Quantitative LC-MS in the Clinical Laboratory
Donald S. Mason
Waters Corporation (Milford, MA)
(PDF slides) (PDF handouts)

SESSION III – Endocrinology

Vitamin D Deficiency and Determination of 25-Hydroxyvitamin D by LC-MS/MS
Peter P. Chou, PhD
Quest Diagnostics Nichols Institute (Chantilly, VA)
(PDF slides) (PDF handouts)

Mass Spec Testing for Steroid Hormone Profiles: Making an Impact on Patient Care
Ravinder J. Singh, PhD
Mayo Clinic (Rochester, MN)
(PDF slides) (PDF handouts)

September 7, 2012

SESSION IV – New Frontiers

Microbiology Applications of Mass Spectrometry
Donna M. Wolk, PhD
University of Arizona (Tucson, AZ)
(PDF slides

Mass Spectrometric Analysis of DNA and RNA: Alternatives to Traditional Sequencing
Mark A. Marzinke, PhD
Johns Hopkins University (Baltimore, MD)
(PDF slides) (PDF handouts)

Quantitation of Peptides and Proteins by Mass Spectrometry
Omar F. Laterza, PhD
Merck, Inc. (Rahway, NJ)
(PDF slides) (PDF handouts)

SESSION V – LC-MS for Drug Analysis

Trends and Challenges in Therapeutic Drug Monitoring
Paul J. Jannetto, PhD
Mayo Clinic (Rochester, MN)
(PDF slides) (PDF handouts)

LC-MS for Pain Management Support
Gwen A. McMillin, PhD
ARUP Laboratories (Salt Lake City, UT)
(PDF slides) (PDF handouts)