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Validation of Clinical LC-MS/MS Methods: What you need to know

  • Credit:1.0 ACCENT
  • Duration: 1 hour
  • Date:NOV.14.2018 1:00 PM - NOV.30.2019 5:00 PM

Price: $0.00

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Clinical laboratories have increasingly adopted LC-MS/MS for its increased sensitivity and specificity over more commonly used analytical techniques. However, implementation can be daunting due to the complex nature of the instrumentation and the need for method development and validation. This webinar will cover examples of how to clinically validate LC-MS/MS methods as well as provide post-implementation monitoring suggestions. 

What you will learn

  • Write a validation plan and pre-validation recommendations.
  • Discuss best practices and solutions for determining common validation parameters such as precision, linearity, matrix effects, extraction recovery and accuracy.
  • Write a validation summary and establish LC-MS/MS data review/reporting criteria.


Deborah FrenchDeborah French, PhD, DABCC (CC, TC), FAACC
Associate Clinical Professor
Assistant Director of Chemistry
Director of Mass Spectrometry
UCSF Clinical Laboratories
San Francisco, CA



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