Marie Browne, PhD
National University of Ireland Galway
Dr. Marie Browne graduated from National University of Ireland Galway with a BSc in Biochemistry in 2007. She subsequently carried out her PhD entitled "Connective Tissue Growth Factor (CTGF) in the initiation and progression of Diabetic Nephropathy" in the Diabetic Complications Research Centre (DCRC), University College Dublin, Ireland. She is currently employed by Randox Teoranta as a research and development scientist where she is involved in biomarker discovery and assay development.
Insulin receptor substrate 2 and FoxO3a signalling are involved in E-cadherin expression and transforming growth factor-β1-induced repression in kidney epithelial cells. Carew RM, Browne MB, Hickey FB, Brazil DP. FEBS J. 2011 Sep;278(18):3370-80. doi: 10.1111/j.1742-4658.2011.08261.x. Epub 2011 Aug 16.
CTGF/CCN2 activates canonical Wnt signalling in mesangial cells through LRP6: implications for the pathogenesis of diabetic nephropathy. Rooney B, O'Donovan H, Gaffney A, Browne M, Faherty N, Curran SP, Sadlier D, Godson C, Brazil DP, Crean J.FEBS Lett. 2011 Feb 4;585(3):531-8. doi: 10.1016/j.febslet.2011.01.004. Epub 2011 Jan 14.