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Recent Artery Conversations

What *is* an LDT?

We are going around and around in our lab about what exactly is a LDT. Does anyone have a formal definition?
Please share.

Discrepancy in ANA Results

I have three patients with very high values of anti-dsDNA antibodies with Bioplex (around 90 IU/ml); however, all of them gave negative ANA IFA by using the ImmunoConcepts HEp-2000 kit. I sent them out for ARUP, and all of them resulted in positive by the IFA assay (i don't know what kit they used). We diluted the specimens (off label) up to 1: 2560 and still got negative results. Does anyone have any suggestions on how we can do a route cause analysis for our negative IFA results? Or have any explanation for this issue?
Please share.

cTnI is a Signature Biomarker for the Heart not the cTnT

The cTnI is a signature biomarker for the heart. However, cTnT is not a signature biomarker for the heart as it is also expressed in skeletal muscle. Therefore, why the hs-cTnT get more traction over cTnI in the emergency department (ED).
Please share.


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