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CLN COVID-19 News banner

This page features CLN’s coverage of the COVID-19 pandemic. All CLN articles on COVID-19 are open access.

Recent CLN Articles

Another Push to Build COVID-19 Testing Capacity

OCT.1.2020 – A portable, reverse transcription polymerase chain reaction (RT-PCR) device that requires no lab processing for results and a paper-based lateral flow immunoassay that operates similarly to a home pregnancy test are among nine new technologies that have joined the National Institutes of Health’s Rapid Acceleration of Diagnostics (RADx) initiative. 

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COVID-19 During Pregnancy

SEPT.17.2020 – Recent clinical data suggest that pregnancy exacerbates SARS-CoV-2 complications. Expectant mothers face stressors to the immune system and to the lungs and heart that increase vulnerability to COVID-19 illness.

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The Case for Mass-Scale COVID-19 Testing

SEPT.17.2020 – As schools and businesses struggle to reopen in the midst of a global pandemic, institutions and test developers have been working on strategies to mass produce and deploy rapid tests, pool samples and step up contact tracing for COVID-19.

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COVID Antigen Testing: An Imperfect but Practical Strategy

SEPT.3.2020 – The SARS-CoV-2 pandemic in America has led to testing shortages, overburdened commercial labs, and slow turnaround times on results. To remedy the supply issue, federal entities, states, and manufacturers have been strategizing on rapid point-of-care antigen tests, assays that deliver quicker but perhaps less accurate results than traditional reverse transcription-polymerase-chain reaction assays.

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Fall Rush

SEPT.1.2020 – How is the coronavirus pandemic affecting how institutions plan for seasonal flu testing? Lab and infectious diseases leaders discuss their testing algorithms, testing assays and collaboration and communication among healthcare professionals in preparation for a typical flu season coupled with the COVID-19 pandemic.

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When a Substance Abuse Crisis and Pandemic Intersect

AUG.20.2020 – Recent statistics indicate that the COVID-19 pandemic is driving drug overdose trends—and deaths. As the pandemic dominates as the top national health and economic concern, clinical labs, federal agencies, and medical groups continue to monitor the opioid crisis, taking steps to tamp down on designer drug use and watch prescription trends.

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Could Innovation Ease the COVID-19 Testing Crunch?

AUG.20.2020 – Researchers and test developers continue to look for unique solutions to shorten the time for returning SARS-CoV-2 test results, as the virus’s aggressive march outpaces testing efforts, particularly in the U.S. Countless projects are underway to deploy rapid assays, at-home tests, and other innovations across the globe.

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COVID-19: The Lab Medicine Residency Challenge

AUG.6.2020 – The COVID-19 global pandemic has impacted every sphere of life including lab medicine residency programs. The author's program at Ram Manohar Lohia Hospital in New Delhi, India is no exception.

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Evidence Checkup on COVID-19 Antibody Tests

AUG.6.2020 – A global consensus is building to more thoroughly vet and improve testing strategies for SARS-CoV-2 antibody assays, whose performance in studies has yielded inconsistent and, at times, poor results.

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A Strategy for Managing Multisystem Inflammatory Syndrome in Children

JULY.16.2020 – The clinical profile of multisystem-inflammatory syndrome in Children (MIS-C), a complication of COVID-19, the illness caused by the SARS-CoV-2 virus, continues to evolve. As studies emerge on the demographics, clinical presentations, and lab values specific to this condition, experts have been crafting algorithms to optimize testing in children suspected of having this novel inflammatory disorder.

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Innovative Technologies Offer Promise of Speedier SARS-CoV-2 Testing

JULY.2.2020 – The race is on to develop innovative tests that rapidly and accurately detect SARs-CoV-2. The launch of the National Institutes of Health’s Rapid Acceleration of Diagnostic Technologies (RADx Tech) program in late April and other recent initiatives underscores this activity. Manufacturers have sprung into action to produce accessible and easy-to-use testing platforms for use in the lab and at home.

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COVID-19 Is a Catalyst for Remote Sampling and Telemedicine

JULY.1.2020 – In response to COVID-19, healthcare is transitioning to at-home procedures to make patient sampling and collection easily accessible. According to Grand View Research, the telemedicine market is expected to be a $155 billion industry by 2027.

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A Path Forward for SARS-CoV-2 Testing

JUNE.18.2020 – SARS-CoV-2 testing options that screen for active illness or past infection have expanded rapidly over the last few months. As institutions craft guidelines on optimizing polymerase chain reaction (PCR) diagnostic tests and serology antibody tests, some labs have been developing their own testing and result reporting algorithms.

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Disseminated Intravascular Coagulation in COVID-19—Insights From the Front Lines

JUNE.4.2020 – Evidence is mounting that seriously ill COVID-19 patients develop coagulation problems, giving rise to disseminated intravascular coagulation (DIC). This alarming trend, leading to strokes and death even among young people, raises questions over the need to treat ICU patients with anticoagulants—and which lab tests most effectively target DIC and monitor bleeding risk from these medications.

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Laboratories Are Rising to the COVID-19 Challenge

JUNE.1.2020 – With the rapid spread of the SARS-CoV-2 virus across the world, hospital laboratories had no choice but to respond as quickly as possible. In facing the pandemic, clinical laboratorians said a renewed sense of teamwork inside their labs, and outside with clinicians and manufacturers, continues to drive their spirited response to the crisis.

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SARS-CoV-2 Testing on AACC Artery—Online Resource for the Global Laboratory Community

MAY.21.2020 – With researchers and clinicians alike continuously learning about SARS-CoV-2, ongoing dialogue among professionals about these issues and more has been crucial. The global lab community has turned time and time again to the SARS-CoV-2 Testing Community on AACC Artery, available to AACC members and other interested parties after a simple registration.

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Diabetes Management in the Time of COVID-19

MAY.21.2020 – Individuals with diabetes are at increased risk for COVID-19, the illness caused by the SARS-CoV-2 virus. As federal officials loosen restrictions on in-hospital use of personal glucose meters by COVID patients, clinical labs and institutions can take critical steps to support patients with diabetes or metabolic disease in the hospital setting.

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The Great COVID-19 Serology Race

MAY.21.2020 – With the notion that serology tests could help identify individuals with past COVID-19 infections and support community surveillance efforts, the Food and Drug Administration first allowed serology tests for SARS-CoV-2 to come to market in March. Developers responded in droves.

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Factors in Implementing SARS-CoV-2 Serology Tests

MAY.7.2020 – Serology tests that detect SARS-CoV-2 virus antibodies (immunoglobulin A/G/M) have proliferated as society looks for ways to relax quarantine restrictions. Such tests might help track community spread of SARS-CoV-2 virus and determine whether plasma donated by patients who have recovered from COVID-19 could help still sick patients recover.

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Key Biomarkers in Managing COVID-19

APR.16.2020 – Common laboratory values may provide key insights into patients with COVID-19, the illness caused by the SARS-CoV-2 virus, as well as the viral infection itself.

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The Race to Bring SARS-CoV-2 Tests Online

APR.16.2020 – Heeding the emergency call by federal regulators to rapidly develop and distribute tests for 2019-novel-coronavirus SARS-CoV-2, diagnostic manufacturers and clinical labs have taken unprecedented steps, surmounting delays and challenges to meet the demands of a global outbreak modern history has never seen.

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Lab Preparedness During the COVID-19 Pandemic

APR.2.2020 – The past few months have been a whirlwind of news about, and activities in response to, the emergence and spread of the novel coronavirus, SARS-CoV-2. As this pandemic unfolds, laboratory personnel are key to the efforts to halt the virus’s spread and treat patients.

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How Labs in the U.S. Are Responding to COVID-19

MAR.18.2020 – With testing in the global spotlight, two laboratorians share their stories of bringing up testing as regulatory hurdles, shortages of test components, and a rapidly expanding pandemic stressed laboratories unlike anything before.

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AACC COVID-19 Resource Center

All of AACC’s education and advocacy resources, the AACC COVID-19 Testing Directory, and more.

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