Issue

Machine learning (ML), which uses predictive modeling tools to inform healthcare decision-making, has made its mark on just about every sector of the healthcare industry, from epidemiology to genomics to oncology. As Tony Badrick, PhD, describes in November’s Clinical Chemistry Q&A, the technique has made specific inroads in image recognition,…

Developers of “prime editing,” a method that leverages RNA to directly “write” human cells into a specific DNA site, believe it has the ability to correct nearly 90% of all known disease-causing genetic variants. In the journal Nature, researchers describe how they used this genomic editing approach to correct with…

A multi-omics analysis from the PTSD Systems Biology Consortium suggests that a set of 28 biomarkers might aid in diagnosing post-traumatic stress disorder (PTSD) in war veterans.

Fentanyl, heroin, and cocaine are the leading culprits in drug-related overdose deaths in the United States, although methamphetamine—the fourth most common cause of overdose deaths nationally—tops the list in many southern and western states, including Texas, Louisiana, Washington, and California, according to a new report from the Centers for Disease…

Researchers at Northwell Health Labs in New York used a five-stage method to develop and implement five process measures that improved turnaround time (TAT) significantly for three key analytes. The mean TAT improved for all three analytes—cardiac troponin T (cTn) , potassium, and complete metabolic panel-albumin (CMP-Alb), dropping in minutes…

Patients with diabetes mellitus, especially those who develop the disease when young and consequently live with it for a long time and who have comorbid conditions, are at elevated risk of cardiovascular disease (CVD). To guide clinicians on preventing and managing the effects of diabetes on the cardiovascular system, the…