Issue

Diagnostic testing could be the linchpin for developing precision prevention, therapeutics, treatments, and prognostics in diabetes, according to an international consensus report.

The clinical profile of multisystem-inflammatory syndrome in Children (MIS-C), a complication of COVID-19, the illness caused by the SARS-CoV-2 virus, continues to evolve. Patients often have elevated C-reactive protein (CRP), D-dimer, and troponin levels, experience symptoms across major organ systems, and in some cases become severely ill. Moreover, MIS-C manifests…

Rapid tests might decrease the rate of antibiotic prescriptions, solidifying their role in stewardship programs. But they seem to have little or no impact on the dispensing of these medications to treat sore throat, according to the authors of a study in the Cochrane Database of Systematic Review.

The COVID-19 pandemic has affected healthcare operations profoundly, and clinical labs are no exception. Fortunately, lab directors have been sharing their experiences and insights to support others dealing with the same issues. Three sets of authors writing in The Journal of Applied Laboratory Medicine elaborate on assessing lab safety risks,…

No systematic review of diagnostic test accuracy is immune to “spin” or overinterpretation, according to the authors of an analysis published in Clinical Chemistry. Researchers in Canada and the Netherlands evaluated diagnostic test accuracy systematic reviews published in high-impact-factor journals and found that nearly 80% had some form of overinterpretation.…

To better identify and treat patients with shrunken pore syndrome (SPS), a common kidney disorder associated with a high mortality rate, one researcher recommends an update to the 2012 Kidney Disease: Improving Global Outcomes (KDIGO) guidelines to include determination of cystatin C as part of the workup for chronic kidney…