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Thursday, March 21, 2019

In The News

Pediatric reference intervals are key to medical decisionmaking, but suffer from errors and large information gaps. In an AACC-sponsored congressional briefing on February 27, leaders in clinical laboratory medicine from the federal and private sectors discussed ways to counter these issues, including increasing access to samples of healthy children covering…
Across a wide spectrum of cancers, advanced testing methods are making headway in measuring circulating tumor DNA (ctDNA) and other biomarkers to assess molecular treatment responses in patients, laying the path for more effective and targeted therapies.

AACC Alert

What was the cause behind a 2018 multistate outbreak of hemorrhaging among synthetic cannabinoid users? The latest issue of Clinical & Forensic Toxicology News (CFTN) reveals that brodifacoum, a second-generation long-acting anticoagulant rodenticide (LAAR) in the warfarin family, may have been the culprit.

CLN Connect

The simple fact is that laboratories can’t accommodate every STAT request. In the March Clinical Laboratory News, Stacy E.F. Melanson, MD, PhD, offers some strategies for tackling a frustrating problem that invariably causes friction between labs and clinicians and has a big impact on patient care. “Expectations and goals for…

Inside AACC

Next-generation sequencing (NGS) is moving beyond core research applications and playing a larger role in biodefense research. A review in the March issue of Clinical Chemistry describes NGS’ current and future applications in this area, the limitations associated with using this technology, and the regulatory challenges it faces.

Practice Management

Routine urinary tract infection tests are among the most commonly ordered lab tests in hospitals, and their excessive utilization raises the risk of unnecessary antibiotic prescriptions and additional healthcare costs. A study conducted by researchers at Washington University School of Medicine in St. Louis demonstrated how a simple reflex algorithm…

World View

A new method that identifies Vibrio cholerae O1 in just a drop of blood could be a game-changer in tracking the path and burden of disease. Researchers published their results in Science Translational Medicine (STM). “Currently, we use serological [blood antibody] assays for the diagnosis and surveillance of several infectious…