Issue

Whole-genome sequencing (WGS) will almost certainly replace gene panels in identifying cancer, calling for new healthcare infrastructures to support this trend in personalized care, argue U.K.-based cancer researchers Jyoti Nangalia, MB BCh, PhD and Peter Campbell, PhD in a New England Journal of Medicine review. Current debates about testing mutations…

A new direct measurement tool suggests that Bisphenol A (BPA) levels in humans are drastically higher than previous estimates, raising new alarms about the safety of this endocrine disrupting chemical (EDC).

A study in The Journal of Clinical Endocrinology & Metabolism found that the condition affects 24 routine blood tests such as lipids, liver function, inflammation markers and iron—70% of the blood tests studied, according to the study’s first author, Victoria Higgins, PhD, of The Hospital for Sick Children and The…

Would molecular diagnostics testing function best in a consolidated or distributed model? In Clinical Chemistry point-counterpoint articles John Longshore, PhD, FACMG, director of molecular pathology at Carolinas Pathology Group, extols the financial and operational advantages of a centralized core lab, while Frederick S. Nolte, PhD, professor of pathology and laboratory…

Clinical laboratory professionals at the Medical College of Georgia at Augusta University (AU) used automation, autoverification, point-of-care (POC) testing, and other strategies to achieve in-lab turnaround time (TAT) of 45 minutes for more than 90% of specimens orderable as STAT, effectively eliminating STAT testing except for “rare exceptions.”

First recognized as a distinct disease in 2003, IgG4-related disease (IgG4-RD) has since evolved from the field of rheumatology to general medicine and other subspecialties, making its mark worldwide.