A 25-year-old male patient presented to the emergency department with a sustained erection (12 h) with severe pain. He had taken ibuprofen and showered with cold water with no improvement. His medications included bupropion and trazodone. The results from 2 consecutive blood samples (18 min apart) drawn from his penis are shown below:



  1. Is penile blood gas the right sample for the patient's condition?
  2. What is the clinical significance of obtaining 2 consecutive samples?
  3. What is the likely cause of the patient's medical condition?

Read the article here ​for the answers.