This webcast originally aired as a live webinar
co-sponsored by AACC and Seattle Children's Hospital on March 4, 2013. As
healthcare providers learn more about how to use the results of whole genome and
exome (the portion of the genome that contains protein-coding genes) sequencing
in clinical care, questions about how to best use the results clinically and
ethically have arisen. On this program, Dr. Holly Tabor describes how exome
sequencing (ES)/whole genome sequencing (WGS) is becoming available and used in
clinical care and research in the pediatric setting and identifies key ethical
challenges in the management of primary and secondary findings from ES/WGS. Dr.
Tabor also describes how a self-directed management approach to ES/WGS results
may maximize benefits and minimize harms.