LC-MS in Drug Analysis
Member Price: $139.00
Liquid-chromatography-mass-spectrometry procedures have
been shown to be successful when applied to drug development and analysis.
LC-MS in Drug Analysis: Methods and Protocols provides detailed
LC-MS/MS procedures for the analysis of several compounds of clinical
significance. The first chapters provide the reader with an overview of mass
spectroscopy, its place in clinical practice, its application of MS to TDM and
toxicology, and the merits of LC-MS(/MS) and new sample preparation techniques.
Additional chapters discuss different approaches to screening for drugs of abuse
and for general unknowns, as well as targeted measurement of specific analytes
or classes of analytes including abused drugs, toxic compounds, and therapeutic
agents. Chapters include introductions to their respective topics, lists of the
necessary materials and reagents, step-by-step, readily reproducible protocols,
and notes on troubleshooting and avoiding known pitfalls. Authoritative and
easily accessible, LC-MS in Drug Analysis: Methods and Protocols
seeks to serve both
professionals and novices with its well-honed methodologies.