Science & Practice
These blood-based tests complement PCR-based diagnostic testing, but they have limitations depending on the timing of a test versus a patient’s antibody response as well as a test’s performance characteristics.
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Current practices, including earlier-than-ideal test timing and treatment decisions based on a single measurement, cited as factors.
AACC guidance stresses the effectiveness of an interdisciplinary committee to ensure a successful program; recommends continual operator training and participation in proficiency testing/external quality assessment initiatives.
AACC urges open communications between laboratory professionals and clinicians to prevent this potentially harmful test confounder.