Andrew Hoofnagle

Mentor Interview

Andrew N. Hoofnagle, MD, PhD

Andrew N. Hoofnagle, MD, PhD, is an assistant professor of laboratory medicine and medicine and director of clinical mass spectrometry at the University of Washington in Seattle. He has pioneered the use of peptide immunoaffinity enrichment-liquid chromatography-tandem mass spectrometry in the measurement of low abundance proteins in clinical samples. He has also used targeted proteomics to better understand lipoprotein metabolism in people at increased risk for cardiovascular disease. Other projects in his laboratory investigate the importance of local complement activation in the development of atherosclerotic lesions as well as the role vitamin D may have in cardiovascular disease. Dr. Hoofnagle serves as associate editor for the journal Clinical Chemistry.