An 85-year-old man was being assessed for multiple sclerosis. The patient's paired cerebrospinal fluid (CSF) and serum samples were sent to the clinical biochemistry laboratory for oligoclonal-band analysis by CSF isoelectric focusing/IgG immunofixation (Fig. 1).
- What is the interpretation for this sample?
- What is the differential diagnosis for multiple bands in the γ-globulin region in CSF?
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