A 15-year-old white girl presented with headaches and night sweats of 2 weeks' duration. Her platelet count was 50 × 103/μL (50 × 109/L) [reference interval, 140–440 × 103/μL (140–440 × 109/L)]. Upon referral to hematology/oncology, the patient had a leukocyte count of 21 × 103/μL (21 × 109/L) [reference interval, 3.8–9.8 × 103/μL (3.8–9.8 × 109/L)] with 46% lymphoblasts. The patient was diagnosed with pre-B acute lymphocytic leukemia and was started on treatment. A follow-up sample for a basic metabolic panel that had been drawn into lithium heparin and centrifuged is shown in Fig. 1.
- Why are data from this type of sample compromised?
- What is the most likely reason for the appearance of this sample?
- What are potential remedies to extract meaningful data from this sample?