An add-on test was ordered for a patient's serum sample. Upon its retrieval from a refrigerator, the sample appeared as a milky white suspension with no visible aggregates or gel-like structures. When the sample was warmed to 37 °C, the color and the appearance of the sample did not revert to those of normal serum. Crystals were observed when the sample was analyzed microscopically (Fig. 1).
- What caused the change in the serum?
- Which diseases cause this phenomenon?
- Can the add-on tests be performed on such a sample?
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