Pediatric Reference Range Initiative

AACC is working to improve the pediatric reference intervals (PRI) used by clinicians and other health care providers to appropriately interpret test results and make critical decisions involving children's health. This initiative, spearheaded by the Association's Pediatric Reference Range Committee (PRRC) and Pediatric and Maternal-Fetal (PMF) Division, is committed to:

  • Educating key stakeholders about the need for new pediatric reference intervals;
  • Fostering greater collaboration and sharing of data among interested parties; and
  • Promoting new research to create the data needed for developing new pediatric reference ranges.

The PRRC is currently working on two studies using blood spots from the NIH National Children's Study to generate new reference ranges for certain amino acids and steroids.

Pediatric Reference Range Committee
David Colantonio, PhD  dcolant1@gmail.com
Dennis Dietzen, PhD Dietzen_D@kids.wustl.edu
Patti Jones, PhD patti.jones@childrens.com
Amy Pyle, PhD Amy.Pyle@nationwidechildrens.org
Joely Straseski, PhD joely.a.straseski@aruplab.com

NIH National Children's Study
In 2000, Congress passed the Children's Health Act (Public Law 106-310), which directs the National Institutes of Health (NIH) to conduct a 20-year study – the National Children's Study (NCS) -- to examine the impact of environmental factors on the health and development of children. The study will examine more than 100,000 children from birth until the age of 21 to determine the root cause of a number of childhood and adult conditions.

Ongoing Pediatric Reference Interval Studies

Key Pediatric Reference Range Sites

CLN Articles

Upcoming Events

  • Open Session at AACC Annual Meeting to Discuss Pediatric Reference Range Initiative (More information forthcoming)

Missing Links
Email us vstine@aacc.org useful Pediatric websites not listed on the AACC site​

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