Each month, a case and a series of questions can be emailed to interested individuals 4-6 weeks in advance of publication. The published version will include a discussion of the case, important points to remember, and comments from 1-2 experts in the field. We urge you to share and discuss these with your trainees each month.

Difficulty Measuring Methotrexate in a Patient with High-Dose Methotrexate–Induced Nephrotoxicity
DOI: 10.1373/clinchem.2010.144824

• Student Discussion Document
• Complete Article
• Commentary: E. Fox and F. Balis
• Commentary: M. Milone 

Increased Homocysteine in a Patient Diagnosed with Marfan Syndrome
DOI: 10.1373/clinchem.2010.147702

• Student Discussion Document
• Complete Article
• Commentary: G. Berry and H. Levy
• Commentary: M.J. Bennett
  

Interpretation of HIV Serologic Testing Results
DOI: 10.1373/clinchem.2009.139535

• Student Discussion Document
• Complete Article
• Commentary: Frederick S. Nolte
• Commentary: Bernard M. Branson
   

A Healthy Young Man Presenting with Multiple Rib Fractures
DOI: 10.1373/clinchem.2009.135095

• Student Discussion Document
• Complete Article
• Commentary: David Sinclair
• Commentary: Sterling T. Bennett

Opiate-Positive Immunoassay Screen in a Pediatric Patient
DOI: 10.1373/clinchem.2009.137596

• Student Discussion Document
• Complete Article
• Commentary: William H. Porter
• Commentary: Jennifer A. Lowry 

Which Dose of Busulfan Is Best?
DOI: 10.1373/clinchem.2009.134940

• Student Discussion Document
• Complete Article
• Commentary: William Clarke
• Commentary: Mark D. Kellogg

Hyperphosphatemia in a 56-Year-Old man with Hypochondrial Pain
DOI: 10.1373/clinchem.2009.136895

• Student Discussion Document
• Complete Article
• Commentary: Vivek Roy
• Commentary: David B. Endres

• Student Discussion Document
• Complete Article
• Commentary: Mitchell G. Scott
• Commentary: Robert H. Christenson