Expert Access - Clinical Significance of Analytes in Non-standard Body Fluids

Deanne Franke

Deanna Franke, PhD, DABCC, MT (ASCP)

Thursday, October 20, 2011
1:00-2:00 pm Eastern (U.S.) time




Clinical Significance of Analytes in Non-standard Body Fluids

Laboratories consistently are challenged to provide accurate and precise answers for medical treatment; however, one challenge faced by many laboratorians is to understand how clinicians use body fluid test results to determine etiology of body fluid accumulation, make diagnoses, and manage outcomes. Despite the absence of FDA-approved and validated methods for analysis of body fluids, there exists some, albeit limited, clinical guidelines and published studies that can facilitate clinical interpretation of body fluid test results.

The following presentation highlights the importance of defining differences between standard and non-standard laboratory tests and body fluids.  In addition, a body fluid glossary provides the framework for understanding the pathogenesis of fluid accumulation and characterizing significant endpoints for clinical decision making.  This information should encourage laboratorians to review their current body fluid test menu and collaborate with physicians to ensure reporting of clinically useful body fluid results.


Dr. Deanna Franke received a BA in Microbiology in 1999 from Miami University (Oxford, OH). In 2000, she completed her BS in Clinical Laboratory Science and became a board certified Medical Technologist from American Society of Clinical Pathology. Dr. Franke earned her MS (2003) and PhD (2005) from the Department of Microbiology and Immunology at University of Louisville (Louisville, KY) and then completed a post-doctoral two year Clinical Chemistry and Toxicology Fellowship at the University of Louisville in 2007.

Since 2007, Dr. Franke has been part of Pathology Consultants of South Broward, LLP (Hollywood, FL) as a PhD Clinical Scientist. Supporting Memorial Healthcare System (MHS), the fifth largest public healthcare system in the United States, she serves as a Technical Director of the Core Laboratory and Toxicology for MHS Clinical Laboratories and supports MHS medical and clinical staff as a clinical consultant.

Dr. Franke became an ABCC diplomate in 2009 and has been a member of AACC and SYCL since 2005. currently, Dr. Franke serves on the Florida Local Section Executive Committee.

Her specific areas of interest include body fluid testing, drug monitoring and toxicology, and clinical informatics.

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