Consultant, Division of Cardiovascular Diseases
Director Clinical Core Laboratory Services
Professor of Medicine
Mayo Clinic College of Medicine
The focus of Dr. Jaffe’s research has been the development and implementation clinically of biomarkers of cardiac injury, hemodynamic stress and coagulation in the acute cardiac care setting. Of late his focus has been mostly on markers of cardiac injury and particularly cardiac troponin and to some extent on hemodynamic stress and particularly natriuretic peptides. He has participated in or directed many of the major national and international guidelines initiatives in these areas which include efforts to define the criteria for the diagnosis of acute myocardial infarction. His research activities include a broad range of involvement from basic investigation, assay development, clinical translation and clinical implementation. Publications at each level, usually with collaborators have been developed. At present he has NIH funding as part of a project to define the changing incidence of AMI in the community and to study the use of novel natriuretic peptides in the setting of acute ischemic heart disease. In addition, Dr. Jaffe directs ongoing efforts collecting blood samples on patients who present to the Emergency Department with symptoms compatible with ischemia.