American Association for Clinical Chemistry
Improving healthcare through laboratory medicine

Clinical Chemistry

Clinical Chemistry is the leading forum for peer-reviewed, original research on innovative practices in today's clinical laboratory. In addition to being the most cited journal in the field (24,297 citations in 2009), Clin Chem has the highest Impact Factor (6.886 in 2010) among journals of clinical chemistry, clinical (or anatomic) pathology, analytical chemistry, and the subspecialties, such as transfusion medicine, and clinical microbiology.

 

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 CCJ Cover Image

 May 2012

 

ON THE COVER: Red blood cells, 3D rendering. During the normal 120-day lifespan of a red blood cell a non-enzymatic reaction occurs between glucose and hemoglobin, forming glycated hemoglobin. Millions of measurements of hemoglobin A1c (HbA1c), the major fraction of glycated hemoglobin, are performed each year in hospital laboratories and point-of-care facilities. This issue of Clinical Chemistry contains an article describing the results of a study of the magnitude of inappropriate requesting of HbA1c in patients with diabetes mellitus. Are these tests being ordered and used appropriately? Are clinicians following the recommendations contained in national guidance documents? Find out the answers to these questions by turning to page 906. Reproduced with permission.(c)Dmitry Sunagatov - Fotolia.com.