American Association for Clinical Chemistry
Better health through laboratory medicine
July 2009 Mentor of the Month: Jay McDonald
Jay M. McDonald, M.D.

Jay M. McDonald, M.D. is currently a Professor in the Department of Pathology at The University of Alabama at Birmingham (UAB) and Director of an NIH funded Center for Metabolic Bone Disease. Dr. McDonald is board certified in Anatomic and Clinical Pathology. 

Dr. McDonald received his Bachelor of Science degree from Tufts University and his Medical Degree from Wayne State University, where he also completed his pathology residency. He then completed an internship in internal medicine at the University of Oregon and an individual NIH postdoctoral research fellowship at Washington University in St. Louis.

His academic career has spanned 33 years and includes Directorship of the Division of Laboratory Medicine in the Departments of Pathology and Medicine at Washington University School of Medicine in St. Louis. Dr. McDonald has received several honors and awards; has served as President of the Academy of Clinical Laboratory Physicians and Scientists; has served on the Institute of Medicine Committee on Creating a Vision for Space Medicine During Travel Beyond Earth Orbit; is currently on the editorial boards of three scientific journals; and was Editor-in-Chief of The American Journal of Pathology, from 2003-2008. Throughout his career, he has made major contributions broadly to basic science and to education and research in clinical pathology.   

Dr.McDonald’s basic research was focused for almost 20 years on signal transduction in insulin action. Over the past 15 years, Dr. McDonald’s research has shifted from diabetes to three other major areas of research. These are bone disease, cancer pathogenesis and AIDS pathogenesis. Throughout this phase of his research career, he continues to focus primarily on the role of calcium and calmodulin as intracellular signal transducers. Dr. McDonald has published over 200 scientific manuscripts.