American Association for Clinical Chemistry
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Do You Remember?  Analyzers of Yesteryear

5/22/2012 9:20 AM | Comments (0) Recommend (4)

By Larry J. Kricka DPhil, FACB, CSci, CChem, FRSC, FRCPath
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​The pace of technological advance in our everyday life seems ever faster – the internet, cell phones, tablets, mp3s, Skyping, email, Tweets, texting, satellite maps, gps, not to mention blogging (!) – these have all emerged in recent memory.  In the clinical laboratory, the pace of change has also...(Read More)
Posted at 5/22/2012 9:20 AM | Tags: Instrumentation/Technology
Which Is the RIGHT Equation for Calculating eGFR?

5/15/2012 9:10 AM | Comments (0) Recommend (39)

By Jack Zakowski, PhD, FACB
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​Which is the RIGHT equation for calculating eGFR?  Unfortunately, the answer may be “that depends”. Creatinine and BUN/Urea have long been used as markers of renal function, though creatinine has more recently gained prominence.  It was recognized a decade ago that there was significant variation ...(Read More)
Posted at 5/15/2012 9:10 AM | Tags: Renal/GI/Hepatic
Pediatric Reference Intervals: Current Gaps and New Initiatives

5/8/2012 11:59 AM | Comments (4) Recommend (44)

By Khosrow Adeli, PhD, FCACB, FACB, DABCC
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​Pediatric healthcare is critically dependent on availability of accurate and precise laboratory tests/biomarkers of pediatric disease, and on availability of "reference intervals" (or “normal values”) to allow appropriate clinical interpretation. Children are not small adults; child deve...(Read More)
Posted at 5/8/2012 11:59 AM | Tags: Special Populations
Lipoproteomics: Will Proteins Be More Important Than Cholesterol?

5/1/2012 9:08 AM | Comments (2) Recommend (98)

By Andrew Hoofnagle, MD, PhD
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​Elevated plasma concentrations of LDL cholesterol lead to increased risk of cardiovascular disease and elevated plasma concentrations of HDL cholesterol represent a negative risk factor for cardiovascular disease. But why? Isn’t cholesterol just cholesterol? Our lipoproteins vary in size, structu...(Read More)
Posted at 5/1/2012 9:08 AM | Tags: CVD/Markers/Risk Factors
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