NACB - Scientific Shorts
NACB - Scientific Shorts (formerly NACB Blog)
By Darci Block, PhD, DABCC
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It is well recognized that a majority of lab testing errors occur in the preanalytical phase prior to the blood sample being placed onto the laboratory analyzer (1).  The frequency at which such errors have been reported is summarized in the following figure, adapted from Cararro et. al. (2). Th...(Read More)
By Patricia M. Jones, PhD, DABCC, FACB
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​In the world of medicine, and especially laboratory medicine, new technologies with new and usually improved capabilities are arising far faster than we can keep up with them.   Those new technologies sometimes revolutionize not only the field they spring up in, but also other, originally unrelate...(Read More)
By Dustin Bunch
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Matrix effects are regarded as the Achilles’ heel of clinical liquid chromatography tandem mass spectrometry (LC-MS/MS). Our laboratory has been developing clinical LC-MS/MS assays since 2006. To aid with assay validation, a protocol was established that included a serious investigation of matrix e...(Read More)
By Xuan Mu, PhD
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Cystic Fibrosis (CF) is one of the most common inherited disorders, primarily caused by mutations of a single gene, CF transmembrane conductance regulator (CFTR). An estimated 1.2 million individuals are tested for CF every year in the US (1). Over 127 mutations are associated with the pathogenesis...(Read More)
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