NACB - Scientific Shorts
NACB - Scientific Shorts (formerly NACB Blog)
By Gregg Wallis, PhD, CMgr.
The classic paradigm of antibody structure is that a single mature plasma cell produces one type of immunoglobulin heavy chain and one type of immunoglobulin light chain. These are combined within the cell to produce a tetrameric molecule composed of two identical heavy chains and two identical lig...(Read More)
By Alison Woodworth, PhD, DABCC, FACB
Sepsis is systemic inflammation due to infection.  It is the most common cause of death in intensive care units (1), with a mortality rate up to 50% depending on severity.  Sepsis can be considered in individuals with systemic inflammatory response syndrome (SIRS) manifested by alterations in at le...(Read More)
By Callum Fraser, PhD
The MDRD (Modification of Diet in Renal Disease) Study equation is widely used to estimate glomerular filtration rate (GFR) and many laboratories report this every time a serum creatinine is requested. However, it has been widely reported that such calculated values underestimate GFR when creatin...(Read More)