NACB - Scientific Shorts
NACB - Scientific Shorts (formerly NACB Blog)
By Gregg Wallis, PhD, CMgr.
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The classic paradigm of antibody structure is that a single mature plasma cell produces one type of immunoglobulin heavy chain and one type of immunoglobulin light chain. These are combined within the cell to produce a tetrameric molecule composed of two identical heavy chains and two identical lig...(Read More)
By Alison Woodworth, PhD, DABCC, FACB
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Sepsis is systemic inflammation due to infection.  It is the most common cause of death in intensive care units (1), with a mortality rate up to 50% depending on severity.  Sepsis can be considered in individuals with systemic inflammatory response syndrome (SIRS) manifested by alterations in at le...(Read More)
By Callum Fraser, PhD
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The MDRD (Modification of Diet in Renal Disease) Study equation is widely used to estimate glomerular filtration rate (GFR) and many laboratories report this every time a serum creatinine is requested. However, it has been widely reported that such calculated values underestimate GFR when creatin...(Read More)