NACB - Scientific Shorts
NACB - Scientific Shorts (formerly NACB Blog)
By Gregg Wallis, PhD, CMgr.
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The classic paradigm of antibody structure is that a single mature plasma cell produces one type of immunoglobulin heavy chain and one type of immunoglobulin light chain. These are combined within the cell to produce a tetrameric molecule composed of two identical heavy chains and two identical lig...(Read More)
By Rojeet Shrestha, MS
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It is now well known that oxidation of lipids and lipoproteins have immense effects on the development of atherosclerosis. Since hydroperoxides are the major products of lipid peroxidation, its identification and measurement can provide valuable information, including primary prevention of coronary...(Read More)
By Julia C. Drees, Ph.D., DABCC
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​An endocrinologist contacted our laboratory to report a patient with discordant TSH results: undetectable TSH by our routine assay, the Siemens ADVIA Centaur TSH3-UL, and normal TSH by an alternate TSH assay, the Abbott Architect. The clinical picture of the patient matched the normal results. We ...(Read More)
By Michael J. Bennett Ph.D., FRCPath, DABCC, FACB
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​A 72 year old female was recently referred to a metabolism clinic (yes at a children’s hospital!) with a very long history of anemia and bone pain that had been monitored but not particularly investigated by numerous internists. She was subsequently found to be deficient in the enzyme glucocerobro...(Read More)
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