American Association for Clinical Chemistry
Better health through laboratory medicine
NACB - Scientific Shorts
NACB - Scientific Shorts (formerly NACB Blog)
By Danyel Tacker
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​Part I: Case Presentation A male in his late teens, lean and non-diabetic, was brought to the Emergency Department by his parents. Over the last several hours, he displayed increasing confusion and lethargy. At the time of presentation, he was stuporous and his function declining. Liver function ...(Read More)
By Julia C. Drees, Ph.D., DABCC
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​An endocrinologist contacted our laboratory to report a patient with discordant TSH results: undetectable TSH by our routine assay, the Siemens ADVIA Centaur TSH3-UL, and normal TSH by an alternate TSH assay, the Abbott Architect. The clinical picture of the patient matched the normal results. We ...(Read More)
By William E. Winter, MD; Lindsay Bazydlo, PhD, and Neil S. Harris, MD
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​Challenge: The patient is a 16 month old male. How should the results of the following hemoglobin electrophoresis be interpreted?   By alkaline gel electrophoresis: 59.5%  hemoglobin A0.6%   hemoglobin F36.6%  hemoglobin S By cation-exchange HPLC BioRad D-10 (Extended Program): hemoglobin A2 ...(Read More)
By Linnea M. Baudhuin, PhD, DABMG
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​Despite the many different clinical applications in the field of pharmacogenetics (PGx), the clinical uptake of pharmacogenetic testing has, for the most part, not yet met expectations. While not all potential PGx applications have robustly proven clinical utility, there are several tests which ha...(Read More)
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