American Association for Clinical Chemistry
Better health through laboratory medicine
NACB - Scientific Shorts
NACB - Scientific Shorts (formerly NACB Blog)
By Joely Straseski, PhD
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A delta check failure, or alert, is defined as a difference between a patient’s present laboratory result and their previous laboratory result. This difference must exceed a predefined limit, within a predefined amount of time. As an example, if two sodium results differ by more than 13 mEq/L withi...(Read More)
By William Winter, MD
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A toddler has a history of severe bleeding with minor trauma. Child abuse was excluded by evaluation of the family. The initial evaluation includes normal PT, PTT, thrombin time, platelet count and PFA-100. What should you next consider and how can the diagnosis be made?   Response: Factor XIII de...(Read More)
By Dina Greene, PhD
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In a perfect world, protein hormones would be expressed, quickly fold into their bioactive conformation and execute their signaling before being rapidly cleared from the body in more or less their native conformation.  Although we don’t live in a perfect world, the process described is often the do...(Read More)
By William Winter, MD
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I received a call from a local pathologist that their lab was receiving requests for 3-hour oral glucose tolerance tests (OGTTs) on children. In addition, insulin levels were to be measured at each of the 4 time points (zero, 1, 2 and 3 hours). This was a challenge to the patients as the children w...(Read More)