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American Association for Clinical Chemistry
Better health through laboratory medicine
Government & Public Affairs
NACB - The AACC Academy
Can Oxidized Triglycerides Be a Risk Factor for Coronary Heart Diseases?
Is There Utility for Inflammatory Biomarkers for the Early Diagnosis of Chronic Kidney Disease?
What Are the Effects of Key Covariates (Age, Sex, Ethnicity) on Reference Values for Fertility Hormones in Healthy Children and Adolescents ?
Four Commonly Utilized Immunoassays Fail to Detect TSH in a Cohort of Euthyroid Patients: Are TSH Assays Hyper-Selective?
Cancer and Tumor Markers
Clinical Translational Science/Proteomics
Government Affairs/Patient Safety
Molecular Pathology and Genetics
New/Other Disease Markers
To Correct or Not to Correct: pH-Adjusted Free Calcium
3/27/2012 9:34 AM |
Christopher McCudden, PhD, DABCC, FACB
Calcium is found in three major forms in circulation: protein-bound, anion-bound, and ionized or free. To begin on a side note, the term “ionized” calcium is somewhat misleading, as even calcium bound to protein or anions is in fact ionized; from here on I’ll refer to unbound calcium as free. Se...(
Posted at 3/27/2012 9:34 AM
Osmolal Gap: The Mother of All Surrogates?
3/20/2012 9:21 AM |
Roger L. Bertholf, PhD, and William E. Winter, MD
Surrogate can be a verb (to appoint a representative), an adjective (providing or receiving nurture or parental care though not related by blood or legal ties), or a noun (a stand-in or substitute). Several laboratory tests function as surrogates for analytes that are difficult or impractical to m...(
Posted at 3/20/2012 9:21 AM | Tags:
Body Fluid Testing in the Clinical Laboratory: Are You Ready for Your Next CAP Inspection?
3/13/2012 8:22 AM |
Darci Block, PhD, DABCC
For decades, many laboratories have performed chemistry testing on non-standard body fluids (NSBF). NSBFs include everything beyond a blood or urine sample, including but not limited to: CSF, pleural, synovial, peritoneal, dialysate, drain, etc (1). However, the majority of tests that labs offer...(
Posted at 3/13/2012 8:22 AM | Tags:
Should I Be Embarrassed That My Mass Spec Assay Uses an Antibody?
3/6/2012 8:29 AM |
Frederick G. Strathmann, PhD, DABCC
The use of mass spectrometry for clinical diagnostics has grown considerably due in large part to the rapid advancements with liquid chromatography-tandem mass spectrometry (LC-MS/MS). More in-depth discussions of clinical mass spectrometry principles and its uses in the clinical laboratory can be...(
Posted at 3/6/2012 8:29 AM | Tags:
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