American Association for Clinical Chemistry
Better health through laboratory medicine
Curious Chemist Questions and Answers

Welcome to the Curious Chemist Q&A for the New York Metro Local Section.

January 2012 Question

QUESTION #1
The pathology of multiple myeloma includes which of the following?

  1. Expanding plasma cell mass
  2. Overproduction of monoclonal immunoglobulins
  3. Production of osteoclast activating factor and other cytokines
  4. All of the above

QUESTION #2
Vitamin D, a cholecalciferol, is obtained from the diet or exposure of skin to sunlight. What is the biologically active form of Vitamin D?

  1. 25-hydroxycholecalciferol (25-OH-D3)
  2. 1,25-dihydroxycholecalciferol (1,25-[OH]2-D3)
  3. Calcitonin
  4. Parathyroid Hormone ( PTH)

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January 2011 Question

QUESTION #1
An alternative to clearance testing, the glomerular filtration rate can be estimated by which method?

  1. Determining 24 hour urinary protein concentration
  2. Calculation based upon plasma creatinine, age, race, and sex
  3. Measurement of 24 hour urinary urea nitrogen
  4. Measurement of 24 hour urinary sodium concentration

QUESTION #2
The study of pharmacogenomics involves which type of testing?

  1. Family studies to determine the inheritance of drug resistance
  2. Testing drugs with cell cultures to determine the minimum toxic dosage
  3. Testing for single nucleotide polymorphisms known to affect drug metabolism
  4. Comparison of dose response curves among family members

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January 2010 Question

A patient has an elevated serum T3, free T4and a very low serum TSH.

Which of the following is the most likely cause of these results?

  1. Primary hyperthyroidism
  2. Secondary hyperthyroidism
  3. Euthyroidwith increased thyroxine-binding proteins
  4. Euthyroidsick syndrome

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