American Association for Clinical Chemistry
Better health through laboratory medicine
Dr. William Clarke

2005 Young Investigator’s Award Winner:
William Clarke, PhD

Dr. William Clarke received his Ph.D. in Analytical Chemistry from the University of Nebraska in Lincoln in 2000, where his research focused on the development of chromatographic immunoassays for free drugs and hormones. This was followed by a post-doctoral fellowship in Clinical Chemistry at the Johns Hopkins School of Medicine, ending in 2002. During the fellowship, Dr. Clarke began his work in urine proteomics, focusing on the development of biomarkers for early detection of renal allograft rejection. This initial work has expanded to include projects involving delayed graft function, renal ischemia, acute tubular necrosis, and renal cancers. Additional research interests include pharmacogenomics, pharmacoproteomics, method development for TDM, and the study of outcomes based on incorporation of new analytical methods. Dr. Clarke has remained at Johns Hopkins, where he is an Assistant Professor in the Department of Pathology, as well as the director of both Point-of-Care Testing and the Drug Assay Laboratory.

Dr. Clarke has published 15 papers in journals such as Analytical Chemistry, Journal of Chromatography, Clinics in Laboratory Medicine, and Annals of Surgery as well as 9 book chapters. He has received research funding from the National Institutes of Health and the Van Slyke Society of AACC.