KEYNOTE PRESENTATION
Randy Scott, PhD has served as Chairman of the Board and Chief Executive Officer since Genomic Health's inception in August 2000. Dr. Scott was a founder of Incyte Corporation, and served Incyte in various roles, including Chairman of the Board from August 2000 to December 2001, President from January 1997 to August 2000, and Chief Scientific Officer from March 1995 to August 2000. Randy holds a BS in Chemistry from Emporia State University and a PhD in Biochemistry from the University of Kansas. Genomic Health, Inc. is an oncology-based biotechnology company that provides clinically validated genomic tests to improve the quality of treatment decisions for patients with cancer. The company employs a sophisticated, quantitative approach to molecular pathology to provide individualized genomic information on the likelihood of disease recurrence and response to therapy. The company was founded in August 2000 and provides services through its certified clinical reference laboratory located at its headquarters in Redwood City, California.
Thursday, March 16
07:15 - 08:00 Breakfast
Welcome and Keynote Presentation
08:00 - 08:10 Welcome
08:10 - 09:00 Keynote Address
Randy Scott, PhD, Genomic Health, Inc.
Sample Preparation
09:00 - 09:45 Developing quality control parameters for microarrays: current practices and future challenges
Andrea Ferreira-Gonzales, Virginia Commonwealth University
09:45 - 10:30 Break/Exhibits/Posters
10:30 - 11:15 Standardization of the molecular diagnostic process: from early homebrew protocols to new integrated pre-analytical systems
Owe Oelmueller, PhD, Qiagen
11:15 - 12:00 The role of micro-fabricated devices in sample preparation for nucleic acid testing
Larry Kricka, DPh, Hospital of the University of Pennsylvania
12:00 - 01:15 Lunch on your own (Exhibits/Posters)
Amplification
01:15 - 02:00 Helicase-Dependent Amplification: an isothermal DNA amplification method derived from nature
Huimin Kong, PhD, BioHelix
02:00 - 02:45 Single Primer Isothermal Amplification (SPIA™): A rapid, high-fidelity linear amplification system for all your DNA and RNA detection need
Nurith Kurn, PhD, Nugen Technologies
02:45 - 04:15 Break/Exhibits/Posters. Meet Poster Authors 04:15 - 04:30 Podium Poster presentation
04:30 - 05:15 The Strange World of Branched DNA Signal Amplification
Mickey S. Urdea, Halteres Associates, LLC
Friday, March 17
07:15 - 08:00 Breakfast
Detection
08:00 - 08:45 Fully integrated microfluidic biochips for electrochemical detection-based DNA microarray
Robin Liu, PhD, CombiMatrix Corp
08:45 - 09:30 Nanoparticle-based bioelectronic detection of DNA hybridization: nanotubes, nanoparticles and nanowires
Joseph Wang, PhD, Arizona State University
09:30 - 10:45 Break/Exhibits/Posters.
(2nd half) Meet Poster Authors (9:30-10:30).
10:45 - 11:30 Better resolution in gene expression: detection of alternative spliced events using microarrays
Richard Einstein, PhD, ExonHit Therapeutics, Inc.
11:30 - 12:15 Highly multiplexed counting of single molecules using Nanostrings
Krassen Dimitrov, PhD
12:15 - 01:30 Lunch on your own (Exhibits/Posters)
Multiplexing 01:30 - 02:15 Gene expression profiling in formalin-fixed, paraffin-embedded tissues: biomarker discovery for cancer prognosis
Dr. Jian-Bing Fan, Ilumina
02:15 - 03:00 High throughput multiplex assays in the clinical setting
Feras Hantash, Quest Diagnostics
03:00 - 04:00 Break/Exhibits/Posters
04:00 - 04:15 Podium poster presentation
04:15 - 05:00 Combining gene expression and genotyping analysis reveals new biological insights into common diseases: The path to systems biology
Carsten Rosenow, Agilent Technologies
06:00 - 08:30 Banquet and Dinner Presentation
Probing For Quicksand: How We Peer a Bit Ahead, Into Tomorrow's World
David Brin
Friday Evening Dinner Speaker:
Dr. David Brin–Scientist, Public Speaker, Author
Dr. David Brin is a scientist (PhD in Space Physics), public speaker and novelist. Join us at the 20th Anniversary dinner as Dr. Brin shares unique insights–serious and humorous–about ways that changing technology may affect our futures. His 1989 ecological thriller, Earth, foreshadowed global warming, cyberwarfare and near-future trends such as the World Wide Web. Come and hear David explore the possibilities around assay and biosensor technologies in the not so distant future. Dr. Brin’s fifteen novels, including New York Times Bestsellers and winners of the Hugo and Nebula awards, have been translated into more than twenty languages. A 1998 Kevin Costner movie was loosely based on Dr. Brin’s novel The Postman. Kiln People explores a near future when people may be able to be in two places at once. A 144-page hardcover, The Life Eaters rocked the world of graphic novels with a stunning and heroic portrayal of an alternate World War II. Brin's non-fiction book, The Transparent Society: Will Technology Make Us Choose Between Freedom and Privacy? won the Freedom of Speech Award of the American Library Association and deals with issues of openness and liberty in the new wired-age.
Saturday, March 18
07:15 - 08:00 Breakfast
7:45 - 8:30 Continental Breakfast
Applications
08:30 - 09:15 The Joy and frustration of introducing pharmacogenetics into a molecular diagnostics reference lab
Elaine Lyon, ARUP
09:15 - 10:00 Pharmacogenetics in oncology: Recent developments and future perspectives in an academic clinical care setting
Ron van Shaik, PhD, Erasmus University Medical Center
10:00 - 10:15 Break
10:15 - 11:00 Taking a Second Look :How will pharmacogenomics improve drug development and public health?
Mike Orr, PhD, CDER/FDA
11:00 - 11:15 Wrap up
Norm Nelson, PhD