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The Drive to Define “Normal”: The 99th Percentile Value of Cardiac Troponin is part of AACC’s 2014 Clinical Chemistry Series of webinars. The Universal Definition of Myocardial Infarction (MI) includes the typical rise and/or fall of cardiac troponin (cTn) with at least one value above the 99th percentile of a healthy reference population, accompanied by at least one of several clinical factors. Although this definition has been the standard since 2000, there has never been a guideline to help clinical laboratories determine how to select a presumably normal population for the establishment of 99th percentile cutoffs for cTn assays. Attend this webinar and learn approaches you can take to defining “normal” individuals for your cTn reference population using clinical and biomarker surrogates.