American Association for Clinical Chemistry
Improving healthcare through laboratory medicine
43rd Annual Oak Ridge Conference - Online Manual



April 14, 2011 - April 15, 2011
Baltimore, Md. United States


 Thursday, April 14, 2011

KEYNOTE PRESENTATION

Evolution of HIV Diagnostic Testing and Continuing Challenges
Bernard Branson, MD
Centers for Disease Control

SESSION I: New Technologies for Infectious Disease Diagnostics 

The Urgent Need for Tuberculosis Case Detection: Biomarker Discovery and Rapid Test Development
Gerd Michel, PhD
Foundation for Innovative New Diagnostics
Geneva, Switzerland

Multi-Analyte Label-Free Infectious Disease and Autoimmune Antibody Detection
David Ralin, PhD
Maven Biotechnologies
Pasadena, Calf.

Rapid, Point-of-Care Microfluidic Nucleic Acid Detection Technologies to Better Control Infections
Michel G. Bergeron, MD, FRCPC
Université Laval
Québec City, Québec

CONTRIBUTED PAPERS

Development of a µ-Total Analysis System for Point-of-care Detection of Influenza A/H1N1 Infection in Human Respiratory Specimens
Catherine Klapperich
Boston University
Boston, Mass.

Optical Profiling: Reagentless Rapid Identification of Bacterial Pathogens
Jennifer Smith, PhD
Claro Scientific  
St. Petersburg, Fla.
 

SESSION II: New Technologies for Quantitative Pathway Mapping in Tissues and Cells

Functional Protein Pathway Network Mapping of Human Cancer: Delivering on the Promise of Personalized Therapy
Emanuel Petricoin, PhD
George Mason University
Manassas, Va.

Beyond IHC: Accurate, Reproducible and Quantitative Measurement of Protein Analyte Concentrations in Fixed Tissue
David L. Rimm, MD, PhD
Yale University School of Medicine
New Haven, Conn.

Cellular Label Free Integrative Pharmacology (CLIP)
Joydeep Lahiri, PhD
Corning Incorporated
Corning, N.Y.

CONTRIBUTED PAPERS
 
Immunodetection of Individual Antigens Captured on an Antibody Microarray Platform by Force-based Atomic Force Microscopy
Lanna Cox
Nanogea Corporation  
Culver City, Calif.

Employing Mass Spectrometry for Large-scale, Targeted, and Quantitative Protein Measurements in Tumor Tissue and Cancer Cell Lines 
Jacob Kennedy 
Fred Hutchinson Cancer Research Center 
Seattle, Wash.


Friday, April 15, 2011

SESSION III: New Sequencing Technologies for Clinical Diagnostics

Diagnostic Applications of Single-Molecule, Real-Time (SMRT™) DNA Sequencing
Stephen Turner, PhD
Pacific Biosystems
Menlo Park, Calif.

Making Inexpensive, Rapid Nanopore Sequencing a Reality
Daniel Branton, PhD
Harvard University
Cambridge, Mass.

PostLight Sequencing with Semiconductor Chips
Jason Myers, PhD
Ion Torrent
South San Francisco, Calif.

CONTRIBUTED PAPERS

Engineered DNA Polymerases Enable Decreased Amplification Bias and Improved Coverage in Illumina Sequencing Workflows
Marelize Cruywagen
Kapa Biosystems
Woburn, Mass.

Rapid genomic analysis at single molecule level using disposable nanochannel arrays.
Paru Deshpande, PhD
BioNanomatrix, Inc.
Philadelphia, Pa.

SPECIAL PRESENTATION

FDA Oversight of Laboratory-developed Tests: A Status Report
Alberto Gutierrez, PhD
U.S. Food and Drug Administration
Silver Spring, Md.

SESSION IIII: Novel Nanotechnology Approaches for Diagnostics

A Novel Molecular Imprint Nanosensor for the Detection of Proteins
Dong Cai, PhD
Boston College
Chestnut Hill, Mass.

Nanoholes on Metal Films: A New Tool for Biosensing
Alexandre G. Brolo, PhD
University of Victoria
British Columbia, Canada

DNA Detection and Analysis with Nanopores in Graphene Membranes
Marija Drndic, PhD
University of Pennsylvania
Philadelphia, Pa.

CONTRIBUTED PAPERS

Immunoassays with Broad Dynamic Ranges based on Combining Digital and Digitally Enhanced Analog Detection of Enzyme Labels
David Duffy
Quanterix Corporation
Cambridge, Mass.

Next Generation Handheld Analyzer for Monitoring and Diagnosing Diseases
Dimitra Georganopoulou, PhD
OHMX Corporation
Evanston, Ill.