American Association for Clinical Chemistry
Improving healthcare through laboratory medicine
Presentations from Personalized Management of Neurological Diseases

Personalized Management of Neurological Diseases

On September 29 and 30, 2005, AACC, in cooperation with the American Epilepsy Society, The Drug Information Association and the Personalized Medicine Coalition, presented a conference: “Personalized Management of Neurological Diseases.” The goal of the program was to bring together clinicians, pharmacologists and laboratorians to share insights and expertise on the contribution each specialty makes to the management of patients with neurological disorders such as epilepsy, pain, bipolar disorder and other conditions. The goal was met by the outstanding program faculty, in a series of presentations and case studies. The speakers PowerPoint presentations are available for downloading below.

These presentations are the property of the presenters. No reproduction or distribution of these materials may be done without the express consent of the presenters, or in the case of published materials, permission of the copyright holder.

Clinical Pharmacology of Pain, Migraine and Neuropathy Management: A Focus on Anticonvulsants - (PDF Format)
Nancy C. Bratanow, MD
Medical Director
Midwest Comprehensive Pain Care
Milwaukee, WI

Biomarkers for TDM (PDF Format)
Bill Clarke, PhD
Director, Drug Assay Laboratory
Assistant Professor of Pathology
Johns Hopkins School of Medicine

Case Studies -- Bipolar and Other Psychiatric Disorders (PDF Format)
Neil B. Sandson, MD
Director, Residency Training, Sheppard Pratt Health System
Clinical Assistant Professor, University of Maryland Medical School, Department of Psychiatry

Epilepsy Case Studies: Issues across the lifespan (PDF Format)
Barry Gidal, PharmD, RPh
Professor of Pharmacy and Neurology
University of Wisconsin

Sheryl Haut, MD, MS
Associate Professor of Clinical Neurology
Director, Neurology Residency Training Program
Albert Einstein College of Medicine

Individualized Medicine in Neurological Disease: Purpose, Potential and Promise (PDF Format)
Gregory L. Kearns, Pharm.D., Ph.D.
Professor of Pediatrics and Pharmacology, University of Missouri – Kansas City
Chief, Division of Pediatric Pharmacology and Medical Toxicology
Children’s Mercy Hospitals and Clinics

Neurological and Psychiatric Drug Interactions: The Cytochrome P450 System and Beyond (PDF Format)
Neil B. Sandson, MD
Director, Residency Training, Sheppard Pratt Health System
Clinical Assistant Professor, University of Maryland Medical School, Department of Psychiatry

Case Studies: Pain, Migraine, Neuropathy (PDF Format)
Gwen McMillin, PhD
ARUP Laboratories
University of Utah
Salt Lake City, Utah

Pharmacogenetics and its potential contribution to personalized management of neurological disease (PDF Format )
Gwen McMillin, PhD
Medical Director, Clinical Toxicology and Trace Elements Laboratory
ARUP Laboratories
University of Utah
Salt Lake City, Utah

Applying TDM To Antiepileptic Drugs (PDF Format)
Harvey J. Kupferberg, Ph.D, Pharm.D.
Kupferberg Consultants, LLC
Retired, Chief Preclinical Pharmacology Section
Epilepsy Branch, NINDS, NIH

A Brief Review of Neurological Disease Management - The Epilepsies (PDF Format)
Jacqueline A. French
Co-Director, PENN Epilepsy Center
Professor of Neurology
University of Pennsylvania

A Brief Review of Neurological Disease Management - Bipolar Disorders and Related Psychiatric Conditions - (PDF Format)
Elliott Richelson, MD
Consultant in Psychiatry and Pharmacology
Mayo Clinic
Jacksonville, FL

Clinical Pharmacology of the Epilepsies: Pharmacodynamics and Pharmacokinetics (PDF Format)
James Cloyd, PharmD
Epilepsy Research and Education Program
College of Pharmacy
University of Minnesota

Closing Comments: Personalizing Management of Patients with Neurological Disorders (PDF Format)
Catherine Hammet-Stabler, PhD
Associate Professor, Pathology and Laboratory Medicine
Univ of North Carolina Chapel Hill
Chapel Hill, NC