Meeting Proceedings

Emerging Technologies for 21st Century Clinical Diagnostics

AACC's 45th Annual Oak Ridge Conference

April 18-19, 2013 * Baltimore, MD

Day 1
Thursday, April 18, 2013

From Innovation to Commercialization: Taking New Technologies from an Academic Laboratory to the Marketplace
David R. Walt, PhD
Tufts University (Medford, MA)
(PDF slides) (PDF handouts)

SESSION I -- Opening the Test Development Spigot: Better, Faster and Cheaper Affinity Reagents

Developing a Next-gen Pipeline for Rapid Recombinant Affinity-reagent Generation
Michael P. Weiner, PhD
AxioMx, Inc. (Branford, CT)
(PDF slides) (PDF handouts)

Protein-based Affinity Reagents
Brian K. Kay, PhD
University of Illinois at Chicago (Chicago, IL)
(PDF slides) (PDF handouts)

Synthetic Polymer Nanoparticles: Abiotic Receptors for Peptides, Proteins and Carbohydrates
Kenneth J. Shea, PhD
(PDF slides) (PDF handouts)


Stimuli-responsive Reagents Enable Rapid Biomarker Capture and Separation
Barrett Nehilla, PhD
Nexgenia, Inc. (Seattle, WA)
(PDF slides) (PDF handouts)

Towards Small Molecule Diagnostics Using Aptamers and Backscattering Interferometry
G. William Jackson, PhD
Base Pair Biotechnologies, Inc. (Houston, TX)
(PDF slides) (PDF handouts)


SESSION II -- Nanopore Assays: DNA, Proteins and Beyond

Single Protein Characterization Methods with Nanopores
Michael Mayer, PhD
University of Michigan (Ann Arbor, MI)
(PDF slides) (No handouts available)

Nanopore Technology for the Analysis of Proteins and DNA
Liviu Movileanu, PhD
Syracuse University (Syracuse, NY)
(PDF slides) (No handouts available)

Biosensor and Chemosensor Applications of Nanopipette Technologies in Single Cells
Nader Pourmand, PhD
University of California at Santa Cruz (Santa Cruz, CA)
(PDF slides) (PDF handouts)

Direct Detection of Bacterial DNA and Viral RNA at Subfemtomolar Concentrations Using Single Molecule Arrays
Linan Song, PhD
Quanterix Corporation (Lexington, MA)
(PDF slides) (PDF handouts)

On the Path to a Random-access LC/MS Workflow: A Novel Approach to Calibration
Donald Cooper, PhD
Waters Corporation (Manchester, United Kingdom)
(PDF slides) (PDF handouts)

(Click here for ALL abstracts - PDF)


Day 2
Friday, April 19, 2013

SESSION III -- POCT/Implantable Sensors

Issues in Implantable vs. Insertable Biosensors
Robin A. Felder, PhD
University of Virginia (Charlottesville, VA)
(PDF slides) (PDF handouts)

Implantable Biosensors for Glucose Monitoring of Diabetic Patients
Diane Burgess, PhD
University of Connecticut (Storrs, CT)
(PDF slides) (PDF handouts)

The Future of Near-Patient Testing
Vicki Smith
Qualcomm Life – Wireless Health Technologies (San Diego, CA)
(PDF slides) (PDF handouts)


A Truly Handheld, Rapid, Sensitive Electrochemical Immunoassay Point-of-Care System
Courtney Nicholson
AgPlus Diagnostics (Bedfordshire, United Kingdom)
(PDF slides) (PDF handouts)

Point-of-Care Multiplexed Molecular Amplification and Visual Detection for HIV-1 and Beta-actin without Electricity
Jennifer Osborn, PhD
PATH (Seattle, WA)
(PDF slides) (PDF handouts)


SESSION IV -- Biomarkers: Buyer Beware
Statistical Issues Affecting Biomarker Reliability
Steven J. Skates, PhD
Harvard School of Medicine (Boston, MA)
(PDF slides) (PDF handouts)

Challenges in Translational Omics: Smart Strategies for Success
Nathan D. Price, PhD
Institute for Systems Biology (Seattle, WA)
(PDF slides) (PDF handouts)

Moving Biomarkers from Discovery through Translation
Daniel W. Chan, PhD
Johns Hopkins University School of Medicine (Baltimore, MD)
(PDF slides) (PDF handouts)


A Next-gen Sequencing Assay for the Simultaneous Detection of Bladder Cancer-associated Protein and DNA Markers
Anthony Shuber
Predictive Biosciences (Lexington, MA)
(PDF slides) (PDF handouts)

Next Generation Multiplexed Protein Screening
David Sloan
Inanovate, Inc. (Somerville, MA)
(PDF slides) (PDF handouts)

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